1,2-Octanediol, 8-(2-octylcyclopropyl)-, dibenzoate

Base Information

• Chemical Name: 1,2-Octanediol, 8-(2-octylcyclopropyl)-, dibenzoate
• CAS No.: 132866-07-0
• Molecular Formula: C33H46O4
• Molecular Weight: 506.726
• Mol file: 132866-07-0.mol

Synonyms:

Chemical Property of 1,2-Octanediol, 8-(2-octylcyclopropyl)-, dibenzoate

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-Octanediol, 8-(2-octylcyclopropyl)-, dibenzoate

There total 3 articles about 1,2-Octanediol, 8-(2-octylcyclopropyl)-, dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (R)-2-hydroxysterculate (13487-77-9) → C33H46O4 (132866-07-0)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / Pd-C / ethanol / 12 h

2: LiAlH₄ / diethyl ether

3: 4-dimethylaminopyridine / pyridine / 12 h / Ambient temperature

With dmap; lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In pyridine; diethyl ether; ethanol;

DOI:10.1246/bcsj.64.3084

Reference yield:

(R)-2-Hydroxy-8-(2-octyl-cyclopropyl)-octanoic acid methyl ester (13487-78-0) → C33H46O4 (132866-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: 4-dimethylaminopyridine / pyridine / 12 h / Ambient temperature

With dmap; lithium aluminium tetrahydride; In pyridine; diethyl ether;

DOI:10.1246/bcsj.64.3084

Reference yield:

(R)-8-(2-Octyl-cyclopropyl)-octane-1,2-diol (132866-08-1) + benzoyl chloride (98-88-4) → C33H46O4 (132866-07-0)

Guidance literature:

With pyridine; dmap;

upstream raw materials:

(R)-8-(2-Octyl-cyclopropyl)-octane-1,2-diol

benzoyl chloride

(R)-2-Hydroxy-8-(2-octyl-cyclopropyl)-octanoic acid methyl ester

methyl (R)-2-hydroxysterculate

Refernces

• 1、 Nakatani, Munehiro,Hase, Tsunao. "Absolute Stereochemistry and Novel Ring-Opening Oxidation of Methyl (R)-2-Hydroxysterculate". . p. 3084 - 3088. Retrieved 2007/10/02.