Silane, benzoyl(1,1-dimethylethyl)dimethyl-

Base Information

• Chemical Name: Silane, benzoyl(1,1-dimethylethyl)dimethyl-
• CAS No.: 132868-67-8
• Molecular Formula: C13H20OSi
• Molecular Weight: 220.387
• DSSTox Substance ID: DTXSID10455441
• Nikkaji Number: J568.906F
• Wikidata: Q82277429
• Mol file: 132868-67-8.mol

Synonyms:Silane, benzoyl(1,1-dimethylethyl)dimethyl-;132868-67-8;tert-Butylbenzoyldimethylsilane;DTXSID10455441

Chemical Property of Silane, benzoyl(1,1-dimethylethyl)dimethyl-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 220.128341792
• Heavy Atom Count: 15
• Complexity: 231

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)C(=O)C1=CC=CC=C1

Technology Process of Silane, benzoyl(1,1-dimethylethyl)dimethyl-

There total 15 articles about Silane, benzoyl(1,1-dimethylethyl)dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-phenyl-2-(tert-butyl dimethylsilyl)-1,3-dithiane (461051-83-2) → (tert-butyldimethylsilyl)(phenyl)methanone (132868-67-8)

Guidance literature:

With chloroamine-T; In methanol; water; acetone; for 0.25h; Ambient temperature;

DOI:10.1055/s-1992-26287

Reference yield: 81.0%

tert-butyl(dimethyl)<α-(2,6-xylylimino)benzyl>silane (157894-18-3) → (tert-butyldimethylsilyl)(phenyl)methanone (132868-67-8)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 15h; Ambient temperature;

Reference yield: 65.0%

[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dichloromethyl]tert-butyldimethylsilane (882882-28-2) + phenylmagnesium bromide → (tert-butyldimethylsilyl)(phenyl)methanone (132868-67-8)

Guidance literature:

[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dichloromethyl]tert-butyldimethylsilane; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.0833333h;

phenylmagnesium bromide; In tetrahydrofuran; hexane; at -78 - 0 ℃;

With pyridine; oxygen; In tetrahydrofuran; hexane; at 0 ℃; for 1h;

DOI:10.1021/ol0600988

upstream raw materials:

2-phenyl-2-(tert-butyl dimethylsilyl)-1,3-dithiane

tert-butyl(dimethyl)<α-(2,6-xylylimino)benzyl>silane

(α,α-bromobenzyl)(tert-butyl)dimethylsilane

[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dichloromethyl]tert-butyldimethylsilane

Downstream raw materials:

(Z)-3,4,5,5,6,6,7,7,8,8,8-Undecafluoro-2-phenyl-oct-3-en-2-ol

1-<(tert-Butyldimethylsilyl)oxy>-1-phenylperfluorohept-1-ene

(Z)-Perfluorohex-1-enyl phenyl ketone

(E)-Perfluorohex-1-enyl phenyl ketone

Refernces

• 1、 Nagy, Audric,Collard, Laurent,Indukuri, Kiran,Leyssens, Tom,Riant, Olivier. "Enantio-, Regio- and Chemoselective Copper-Catalyzed 1,2-Hydroborylation of Acylsilanes". supporting information. p. 8705 - 8708. Retrieved 2019/06/13.
• 2、 Ishida, Kento,Tobita, Fumiya,Kusama, Hiroyuki. "Lewis Acid-Assisted Photoinduced Intermolecular Coupling between Acylsilanes and Aldehydes: A Formal Cross Benzoin-Type Condensation". supporting information. p. 543 - 546. Retrieved 2017/12/07.