2-benzyl-2-hydroxypentanedioic acid 1-{[3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonyl(methyl)amino)phenyl]amide} 5-[((1S,2R)-2-hydroxyindan-1-yl)amide]

Base Information

Chemical Name:2-benzyl-2-hydroxypentanedioic acid 1-{[3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonyl(methyl)amino)phenyl]amide} 5-[((1S,2R)-2-hydroxyindan-1-yl)amide]
CAS No.:1187975-75-2
Molecular Formula:C₃₈H₄₁FN₄O₇S
Molecular Weight:716.831
Hs Code.:

2-benzyl-2-hydroxypentanedioic acid 1-{[3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonyl(methyl)amino)phenyl]amide} 5-[((1S,2R)-2-hydroxyindan-1-yl)amide]

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Chemical Property of 2-benzyl-2-hydroxypentanedioic acid 1-{[3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonyl(methyl)amino)phenyl]amide} 5-[((1S,2R)-2-hydroxyindan-1-yl)amide]

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Technology Process of 2-benzyl-2-hydroxypentanedioic acid 1-{[3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonyl(methyl)amino)phenyl]amide} 5-[((1S,2R)-2-hydroxyindan-1-yl)amide]

There total 1 articles about 2-benzyl-2-hydroxypentanedioic acid 1-{[3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonyl(methyl)amino)phenyl]amide} 5-[((1S,2R)-2-hydroxyindan-1-yl)amide] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1187975-72-9
2-benzyl-5-oxotetrahydrofuran-2-carboxylic acid [3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonylmethylamino)phenyl]amide

: 7480-35-5,13286-59-4,74165-73-4,126456-43-7,136030-00-7,140632-19-5,140632-20-8
(1S,2R)-1-amino-2-indanol

: 1187975-75-2
2-benzyl-2-hydroxypentanedioic acid 1-{[3-[(R)-1-(4-fluorophenyl)ethylcarbamoyl]-5-(methanesulfonyl(methyl)amino)phenyl]amide} 5-[((1S,2R)-2-hydroxyindan-1-yl)amide]

Guidance literature:: With 2-hydroxypyridin; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; for 72h; Reflux;
DOI:10.1016/j.bmcl.2009.06.065