Ethanone, 1-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]-

Base Information

• Chemical Name: Ethanone, 1-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]-
• CAS No.: 132948-69-7
• Molecular Formula: C₁₅H₂₁NO₄
• Molecular Weight: 279.336
• DSSTox Substance ID: DTXSID80392814
• Nikkaji Number: J1.007.727C
• ChEMBL ID: CHEMBL146671
• Mol file: 132948-69-7.mol

Synonyms:132948-69-7;CHEMBL146671;Ethanone, 1-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]-;1-[4-(2-hydroxy-3-morpholin-4-ylpropoxy)phenyl]ethanone;DTXSID80392814;BDBM50134981;STK966299;AKOS001655227;AKOS016287591;4'-(2-Hydroxy-3-morpholinopropoxy)acetophenone;1-(4-(2-hydroxy-3-morpholinopropoxy)phenyl)ethanone;1-[4-(2-Hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone;1-{4-[2-hydroxy-3-(morpholin-4-yl)propoxy]phenyl}ethanone

Chemical Property of Ethanone, 1-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]-

Chemical Property:

• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 279.14705815
• Heavy Atom Count: 20
• Complexity: 296

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C1=CC=C(C=C1)OCC(CN2CCOCC2)O

Technology Process of Ethanone, 1-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]-

There total 2 articles about Ethanone, 1-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

morpholine (110-91-8,99108-56-2) + 1-[4-(2-oxiranylmethoxy)phenyl]-1-ethanone (19152-55-7) → 1-[4-(2-Hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone (132948-69-7)

Guidance literature:

In ethanol; for 8h; Heating;

Reference yield:

sodium 4-acetylphenolate (3019-86-1) → 1-[4-(2-Hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone (132948-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 6 h / Ambient temperature

2: 66 percent / ethanol / 8 h / Heating

In ethanol;

upstream raw materials:

morpholine

1-[4-(2-oxiranylmethoxy)phenyl]-1-ethanone

sodium 4-acetylphenolate