Biotin-PEG3-NHS ester

Base Information

Chemical Name:Biotin-PEG3-NHS ester
CAS No.:1253286-56-4
Molecular Formula:C₂₃H₃₆N₄O₉S
Molecular Weight:544.626
Hs Code.:2934999090
Mol file:1253286-56-4.mol

Synonyms:

Suppliers and Price of Biotin-PEG3-NHS ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

purepeg
(+)-Biotin-PEG3-NHSEster min.97%
1 g
$ 530.00

BroadPharm
Biotin-PEG3-NHSester 98%
1 G
$ 540.00

Total 8 raw suppliers

Chemical Property of Biotin-PEG3-NHS ester

Chemical Property:

PKA:13.90±0.40(Predicted)
Density:1.35±0.1 g/cm3(Predicted)

Purity/Quality:

98%,99%, ^*data from raw suppliers

(+)-Biotin-PEG3-NHSEster min.97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Biotin-PEG3-NHS ester is an biotinylation compound that can couple with primary amino groups (-NH2). The NHS group reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds.

Technology Process of Biotin-PEG3-NHS ester

There total 7 articles about Biotin-PEG3-NHS ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 252881-76-8
biotin-PEG₃-acid

: 1253286-56-4,365441-71-0
2,5-dioxopyrrolidin-1-yl 14-oxo-18-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-13-azaoctadecanoate

Guidance literature:: With diisopropyl-carbodiimide; In dichloromethane; at 20 ℃;

Reference yield:

: 252881-74-6,872340-65-3
tert-butyl 3-(2-(2-(2-aminoethoxyl)ethoxy)ethoxy)propanoate

: 1253286-56-4,365441-71-0
2,5-dioxopyrrolidin-1-yl 14-oxo-18-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-13-azaoctadecanoate

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane / 20 °C

2: trifluoroacetic acid / dichloromethane / 20 °C

3: diisopropyl-carbodiimide / dichloromethane / 20 °C

With trifluoroacetic acid; diisopropyl-carbodiimide; In dichloromethane;

Reference yield:

: 58-85-5,22879-79-4
biotin

: 1253286-56-4,365441-71-0
2,5-dioxopyrrolidin-1-yl 14-oxo-18-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-13-azaoctadecanoate

Guidance literature:: Multi-step reaction with 4 steps

1: diisopropyl-carbodiimide / N,N-dimethyl-formamide / 45 °C

2: dichloromethane / 20 °C

3: trifluoroacetic acid / dichloromethane / 20 °C

4: diisopropyl-carbodiimide / dichloromethane / 20 °C

With trifluoroacetic acid; diisopropyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide;