Zofluza intermediate

Base Information Edit

Chemical Name:Zofluza intermediate
CAS No.:1985607-83-7
Molecular Formula:C₁₄H₁₀F₂OS
Molecular Weight:264.296
Hs Code.:
Mol file:1985607-83-7.mol

Synonyms:

Suppliers and Price of Zofluza intermediate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol 95%+
1000g
$ 4160.00

Total 72 raw suppliers

Chemical Property of Zofluza intermediate Edit

Chemical Property:

Boiling Point:379.5±42.0 °C(Predicted)
PKA:12.57±0.20(Predicted)
Density:1.400±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Zofluza intermediate

There total 37 articles about Zofluza intermediate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 2136287-66-4
7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepin-11-one

: 1985607-83-7
7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepine-11-ol

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 - 50 ℃; for 5h; Solvent; Large scale;
DOI:10.1021/acs.oprd.9b00389

Reference yield: 93.7%

: 2136287-66-4
7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepin-11-one

: 1985607-83-7
7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepine-11-ol

Guidance literature:: With borane-THF; (S)-5,5-diphenyl-2-methoxy-3,4-propano-1,3,2-oxazaborolidine; In toluene; at 20 - 30 ℃; for 1.5h; Reagent/catalyst; Solvent; Temperature; enantioselective reaction; Inert atmosphere;