4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ethyl ester hydrochloride

Base Information

• Chemical Name: 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ethyl ester hydrochloride
• CAS No.: 1211512-51-4
• Molecular Formula: C₉H₁₃N₃O₂*ClH
• Molecular Weight: 231.682
• Hs Code.: 2933399990
• Mol file: 1211512-51-4.mol

Synonyms:

Chemical Property of 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ethyl ester hydrochloride

Chemical Property:

• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylicAcidEthylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ethyl ester hydrochloride

There total 3 articles about 4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid ethyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5‐tert‐butyl 3‐ethyl 1,4,6,7‐tetrahydro‐5H‐pyrazolo[4,3‐c]pyridine‐3,5‐dicarboxylate (518990-23-3) → C9H13N3O2*ClH (1211512-51-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 15 ℃; for 1h;

Reference yield:

N-tert-butyloxycarbonylpiperidin-4-one (79099-07-3) → C9H13N3O2*ClH (1211512-51-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: 2.5 h / 25 °C / Inert atmosphere

2.1: acetic acid; hydrazine hydrate / 1 h / 80 °C / Inert atmosphere

3.1: hydrogenchloride / 1,4-dioxane / 1 h / 15 °C

With hydrogenchloride; hydrazine hydrate; acetic acid; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

tert-butyl 3-(2-ethoxy-2-oxo-acetyl)-4-oxo-piperidine-1-carboxylate (518990-24-4) → C9H13N3O2*ClH (1211512-51-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; hydrazine hydrate / 1 h / 80 °C / Inert atmosphere

2: hydrogenchloride / 1,4-dioxane / 1 h / 15 °C

With hydrogenchloride; hydrazine hydrate; acetic acid; In 1,4-dioxane;

upstream raw materials:

N-tert-butyloxycarbonylpiperidin-4-one

tert-butyl 3-(2-ethoxy-2-oxo-acetyl)-4-oxo-piperidine-1-carboxylate

5‐tert‐butyl 3‐ethyl 1,4,6,7‐tetrahydro‐5H‐pyrazolo[4,3‐c]pyridine‐3,5‐dicarboxylate

Refernces