Technology Process of C19H16N2O3
There total 1 articles about C19H16N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
trans-3-indole-acrylic acid;
With
N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.333333h;
Inert atmosphere;
2-carbomethoxyaniline;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 4.5h;
Inert atmosphere;
DOI:10.1039/c2ob27114a
- Guidance literature:
-
C19H16N2O3;
With
lithium hydroxide;
In
tetrahydrofuran; water;
at 20 ℃;
With
hydrogenchloride;
In
tetrahydrofuran; water;
DOI:10.1039/c2ob27114a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium hydroxide / water; tetrahydrofuran / 20 °C
2.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.33 h / Inert atmosphere
2.2: 20 °C / Inert atmosphere
3.1: potassium carbonate / tetrahydrofuran / 0.33 h / 20 °C / Inert atmosphere
3.2: 0 - 50 °C / Inert atmosphere
With
potassium carbonate; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; lithium hydroxide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1039/c2ob27114a
