Carbonic acid, 3-(difluoromethyl)-4-methylphenyl 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbonic acid, 3-(difluoromethyl)-4-methylphenyl 1,1-dimethylethyl ester
CAS No.:133409-96-8
Molecular Formula:C13H16F2O3
Molecular Weight:258.265
Hs Code.:

Synonyms:

Suppliers and Price of Carbonic acid, 3-(difluoromethyl)-4-methylphenyl 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbonic acid, 3-(difluoromethyl)-4-methylphenyl 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbonic acid, 3-(difluoromethyl)-4-methylphenyl 1,1-dimethylethyl ester

There total 7 articles about Carbonic acid, 3-(difluoromethyl)-4-methylphenyl 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34265-55-9
ethyl 3-hydroxy-6-methylbenzoate

: 133409-96-8
1-tert-Butoxycarbonyloxy-3-difluoromethyl-4-methylbenzene

Guidance literature:: Multi-step reaction with 6 steps

1: NaI, K₂CO₃ / acetone / Heating

2: DIBAL / toluene / 0 °C

3: (COCl)2, DMSO, NEt₃ / CH₂Cl₂

4: 90 percent / diethylaminosulfur trifluoride / CH₂Cl₂ / 16 h / Ambient temperature

5: CF₃CO₂H / CH₂Cl₂ / 1 h / Ambient temperature

6: Et₃N, DMAP / tetrahydrofuran / 1 h / Ambient temperature

With dmap; oxalyl dichloride; diethylamino-sulfur trifluoride; diisobutylaluminium hydride; potassium carbonate; dimethyl sulfoxide; triethylamine; trifluoroacetic acid; sodium iodide; In tetrahydrofuran; dichloromethane; acetone; toluene;
DOI:10.1016/S0040-4039(00)92112-9

Reference yield:

: 133409-95-7
1-(4-Methoxybenzyloxy)-3-formyl-4-methylbenzene

: 133409-96-8
1-tert-Butoxycarbonyloxy-3-difluoromethyl-4-methylbenzene

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / diethylaminosulfur trifluoride / CH₂Cl₂ / 16 h / Ambient temperature

2: CF₃CO₂H / CH₂Cl₂ / 1 h / Ambient temperature

3: Et₃N, DMAP / tetrahydrofuran / 1 h / Ambient temperature

With dmap; diethylamino-sulfur trifluoride; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)92112-9

Reference yield:

: 139191-91-6
1-(4-Methoxybenzyloxy)-3-hydroxymethyl-4-methylbenzene

: 133409-96-8
1-tert-Butoxycarbonyloxy-3-difluoromethyl-4-methylbenzene

Guidance literature:: Multi-step reaction with 4 steps

1: (COCl)2, DMSO, NEt₃ / CH₂Cl₂

2: 90 percent / diethylaminosulfur trifluoride / CH₂Cl₂ / 16 h / Ambient temperature

3: CF₃CO₂H / CH₂Cl₂ / 1 h / Ambient temperature

4: Et₃N, DMAP / tetrahydrofuran / 1 h / Ambient temperature

With dmap; oxalyl dichloride; diethylamino-sulfur trifluoride; dimethyl sulfoxide; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)92112-9