(7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide)

Base Information

• Chemical Name: (7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide)
• CAS No.: 1443006-59-4
• Molecular Formula: Br*C₄₈H₄₃N₁₀O₄
• Molecular Weight: 903.838
• Mol file: 1443006-59-4.mol

Synonyms:

Chemical Property of (7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide)

There total 3 articles about (7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

pyridine (110-86-1) + C43H38BrN9O4 → (7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide) (1443006-59-4)

Guidance literature:

at 45 ℃; for 9h;

DOI:10.1039/c3ob40519b

Reference yield:

7,16-bis[2-(3-bromopropoxy)benzoyl]-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine (1160848-61-2) → (7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide) (1443006-59-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 20 °C

1.2: 3.08 h / 20 - 40 °C

2.1: 9 h / 45 °C

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1039/c3ob40519b

Reference yield:

adenine (66224-66-6,66224-67-7,66224-68-8,66224-69-9,134434-48-3,134434-49-4,134454-76-5,134461-75-9) → (7-{2-[3-(aden-9-yl)propoxy]benzoyl}-16-{2-[3-(N-pyridinium-1-yl)propoxy]benzoyl}-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine bromide) (1443006-59-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 20 °C

1.2: 3.08 h / 20 - 40 °C

2.1: 9 h / 45 °C

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1039/c3ob40519b

upstream raw materials:

pyridine

7,16-bis[2-(3-bromopropoxy)benzoyl]-5,14-dihydrodibenzo[b,i][1,4,8,11]tetraazacyclotetradecine

adenine