UNC0379 (trifluoroacetate)

Base Information

Chemical Name:UNC0379 (trifluoroacetate)
CAS No.:1620401-83-3
Molecular Formula:(x)C₂HF₃O₂*C₂₃H₃₅N₅O₂
Molecular Weight:527.59
Hs Code.:
Mol file:1620401-83-3.mol

Synonyms:

Suppliers and Price of UNC0379 (trifluoroacetate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
UNC0379trifluoroacetate >98%
1 g
$ 2000.00

DC Chemicals
UNC0379trifluoroacetate >98%
100 mg
$ 500.00

ChemScene
UNC0379TFA 99.91%
5mg
$ 120.00

ChemScene
UNC0379TFA 99.91%
2mg
$ 80.00

Biorbyt Ltd
UNC0379 trifluoroacetate
250 mg
$ 1504.50

Biorbyt Ltd
UNC0379 trifluoroacetate
100 mg
$ 765.00

Total 4 raw suppliers

Chemical Property of UNC0379 (trifluoroacetate)

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

UNC0379trifluoroacetate >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of UNC0379 (trifluoroacetate)

There total 3 articles about UNC0379 (trifluoroacetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 123-75-1
pyrrolidine

: 2-chloro-6,7-dimethoxy-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine

: 76-05-1
trifluoroacetic acid

: 1620401-83-3
6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine trifluoroacetic acid

Guidance literature:: pyrrolidine; 2-chloro-6,7-dimethoxy-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine; With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 160 ℃; for 0.5h; Microwave irradiation;

trifluoroacetic acid; In methanol; water;
DOI:10.1021/jm500871s

Reference yield:

: 27631-29-4
2-chloro-6,7-dimethoxy-3H-quinazolin-4-one

: 1620401-83-3
6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine trifluoroacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 6 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / butan-1-ol / 0.5 h / 160 °C / Microwave irradiation

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; butan-1-ol;
DOI:10.1021/jm500871s

Reference yield:

: 71302-71-1
5-(pyrrolidin-1-yl)pentan-1-amine

: 1620401-83-3
6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine trifluoroacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 6 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / butan-1-ol / 0.5 h / 160 °C / Microwave irradiation

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; butan-1-ol;
DOI:10.1021/jm500871s