6-chloro-4-(ethylamino)-3-Pyridinemethanol

Base Information Edit

Chemical Name:6-chloro-4-(ethylamino)-3-Pyridinemethanol
CAS No.:959162-99-3
Molecular Formula:C₈H₁₁ClN₂O
Molecular Weight:186.641
Hs Code.:
Mol file:959162-99-3.mol

Synonyms:

Suppliers and Price of 6-chloro-4-(ethylamino)-3-Pyridinemethanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 10 raw suppliers

Chemical Property of 6-chloro-4-(ethylamino)-3-Pyridinemethanol Edit

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of 6-chloro-4-(ethylamino)-3-Pyridinemethanol

There total 5 articles about 6-chloro-4-(ethylamino)-3-Pyridinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 959162-97-1
6-chloro-4-ethylamino-nicotinic acid ethyl ester

: 959162-99-3
(6-chloro-4-(ethylamino)pyridin-3-yl)methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Inert atmosphere; Cooling with ice;

Reference yield:

: 40296-46-6
ethyl 4,6-dichloronicotinate

: 959162-99-3
(6-chloro-4-(ethylamino)pyridin-3-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: water; acetonitrile / 0 - 20 °C

2: lithium aluminium tetrahydride / water; tetrahydrofuran / 1 h / -50 - 0 °C

With lithium aluminium tetrahydride; In tetrahydrofuran; water; acetonitrile;

Reference yield:

: 105-50-0
diethyl 1,3-acetonedicarboxylate

: 959162-99-3
(6-chloro-4-(ethylamino)pyridin-3-yl)methanol

Guidance literature:: Multi-step reaction with 4 steps

1.1: orthoformic acid triethyl ester / 2 h / 120 °C

1.2: 0 - 20 °C

2.1: trichlorophosphate / 2 h / Reflux

3.1: water; acetonitrile / 0 - 20 °C

4.1: lithium aluminium tetrahydride / water; tetrahydrofuran / 1 h / -50 - 0 °C

With lithium aluminium tetrahydride; orthoformic acid triethyl ester; trichlorophosphate; In tetrahydrofuran; water; acetonitrile;