5-Isoxazolecarboxylicacid,3-(1-methylethyl)-,methylester(9CI)

Base Information

• Chemical Name: 5-Isoxazolecarboxylicacid,3-(1-methylethyl)-,methylester(9CI)
• CAS No.: 133674-35-8
• Molecular Formula: C8H11NO3
• Molecular Weight: 169.17800
• Hs Code.: 2934999090
• Mol file: 133674-35-8.mol

Synonyms:3-isopropylisoxazole-5-carboxylic acid methyl ester;5-Isoxazolecarboxylicacid,3-(1-methylethyl)-,methylester(9CI);

Chemical Property of 5-Isoxazolecarboxylicacid,3-(1-methylethyl)-,methylester(9CI)

Chemical Property:

• PSA: 52.33000
• LogP: 1.58460

Purity/Quality:

Methyl 3-isopropylisoxazole-5-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Isoxazolecarboxylicacid,3-(1-methylethyl)-,methylester(9CI)

There total 3 articles about 5-Isoxazolecarboxylicacid,3-(1-methylethyl)-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

→ methyl 3-isopropylisoxazole-5-carboxylate (133674-35-8)

Guidance literature:

Reference yield:

aqueous sodium hypochlorite + 2-methylpropionamide oxime (5780-39-2) + propynoic acid methyl ester (922-67-8) → methyl 3-isopropylisoxazole-5-carboxylate (133674-35-8)

Guidance literature:

In dichloromethane;

Reference yield:

C21H20NO4Pol → methyl 3-isopropylisoxazole-5-carboxylate (133674-35-8)

Guidance literature:

With sodium methylate; In tetrahydrofuran; methanol; at 70 ℃; for 18h; solid phase reaction;

DOI:10.1080/00397911.2011.580641

upstream raw materials:

2-methylpropionamide oxime

propynoic acid methyl ester