3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-aminopropyl ester

Base Information

Chemical Name:3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-aminopropyl ester
CAS No.:80691-94-7
Molecular Formula:C₁₄H₂₀ClNO₂
Molecular Weight:269.771
Hs Code.:

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Chemical Property of 3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-aminopropyl ester

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Technology Process of 3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-aminopropyl ester

There total 2 articles about 3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-aminopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.9%

: 80692-06-4
3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-oxopropyl ester

: 80691-94-7
3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-aminopropyl ester

Guidance literature:: With ammonium acetate; 3 A molecular sieve; sodium cyanoborohydride; acetic acid; In methanol; for 30h; Ambient temperature;

Reference yield:

: 57145-14-9
α-(4-Chloro-benzyl)-isobutyric acid

: 80691-94-7
3-(4-chlorophenyl)-2,2-dimethylpropanoic acid 2-aminopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) potassium carbonate / 1.) HMPT; 2.) 3 d

2: 13.9 percent / ammonium acetate, sodium cyanoborohydride, acetic acid, molecular sieves (3 Angstroem) / methanol / 30 h / Ambient temperature

With ammonium acetate; 3 A molecular sieve; sodium cyanoborohydride; potassium carbonate; acetic acid; In methanol;