(3,5-Dichlorophenyl)(4-methoxyphenyl)methanone

Base Information

Chemical Name:(3,5-Dichlorophenyl)(4-methoxyphenyl)methanone
CAS No.:13395-62-5
Molecular Formula:C14H10Cl2O2
Molecular Weight:281.138
Hs Code.:
DSSTox Substance ID:DTXSID501246202
Nikkaji Number:J3.326.426G
Mol file:13395-62-5.mol

Synonyms:(3,5-dichlorophenyl)(4-methoxyphenyl)methanone;13395-62-5;SCHEMBL9360184;DTXSID501246202;(3,5-Dichloro-phenyl)-(4-methoxy-phenyl)-methanone

Suppliers and Price of (3,5-Dichlorophenyl)(4-methoxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3,5-Dichlorophenyl)(4-methoxyphenyl)methanone

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:280.0057849
Heavy Atom Count:18
Complexity:278

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)C2=CC(=CC(=C2)Cl)Cl

Technology Process of (3,5-Dichlorophenyl)(4-methoxyphenyl)methanone

There total 4 articles about (3,5-Dichlorophenyl)(4-methoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 2905-62-6
3,5-dichlorobenzoyl chloride

: 5720-07-0
4-methoxyphenylboronic acid

: 13395-62-5
3,5-Dichlor-4'-methoxy-benzophenon

Guidance literature:: With potassium carbonate; In toluene; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/aoc.3280

Reference yield:

: 13395-68-1
3,5-Dichlor-4'-methoxy-benzhydrol

: 13395-62-5
3,5-Dichlor-4'-methoxy-benzophenon

Guidance literature:: With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 20 ℃; for 3h; Schlenk technique;
DOI:10.1002/anie.202109447

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 13395-62-5
3,5-Dichlor-4'-methoxy-benzophenon

Guidance literature:: Multi-step reaction with 2 steps

1.1: magnesium / tetrahydrofuran; ethylene dibromide / 2 h / Schlenk technique; Inert atmosphere; Reflux

1.2: 1 h / 0 °C / Schlenk technique; Inert atmosphere

2.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide / 3 h / 20 °C / Schlenk technique

With magnesium; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dimethyl sulfoxide; ethylene dibromide;
DOI:10.1002/anie.202109447