(1R,4R)-tert-butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Base Information

Chemical Name:(1R,4R)-tert-butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
CAS No.:134003-83-1
Molecular Formula:C17H24N2O2
Molecular Weight:288.39
Hs Code.:
Mol file:134003-83-1.mol

Synonyms:(R,R)-5-benzyl-2-(tertbutyloxycarbonyl)-2,5-diazabicyclo[2.2.1] heptane;(1R,4R)-tert-butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate;2-(tert-butyloxycarbonyl)5-phenylmethyl-(1R,4R)-2,5-diazabicyclo[2.2.1]heptane;(1R,4R)-2-boc-5-benzyl-2,5-diazabicyclo[2.2.1]heptane;tert-butyl(1R,4R)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate;

Suppliers and Price of (1R,4R)-tert-butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(1R,4R)-tert-Butyl5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate 97%
5g
$ 510.00

Crysdot
(1R,4R)-tert-Butyl5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate 97%
1g
$ 190.00

Chemenu
(1R,4R)-tert-Butyl5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate 95+%
5g
$ 477.00

American Custom Chemicals Corporation
(1R,4R)-TERT-BUTYL-5-BENZYL-2,5-DIAZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE 95.00%
5MG
$ 504.54

Alichem
(1R,4R)-tert-Butyl5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
5g
$ 504.90

Alichem
(1R,4R)-tert-Butyl5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1g
$ 205.20

AK Scientific
tert-butyl(1R,4R)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1g
$ 419.60

Total 13 raw suppliers

Chemical Property of (1R,4R)-tert-butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Chemical Property:

Boiling Point:377.4±35.0 °C(Predicted)
PKA:9.17±0.20(Predicted)
PSA：32.78000
Density:1.140±0.06 g/cm3(Predicted)
LogP:2.75600

Purity/Quality:

97% ^*data from raw suppliers

(1R,4R)-tert-Butyl5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1R,4R)-tert-butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

There total 17 articles about (1R,4R)-tert-butyl 5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 116258-17-4
(1R,4R)-5-phenylmethyl-2,5-diazabicyclo[2.2.1] heptane dihydrobromide

: 134003-83-1
tert-butyl (1R,4R)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 71.0%

: 24424-99-5
di-tert-butyl dicarbonate

: (1R,4R)-5-benzoyl-2,5-diazabicyclo[2.2.1]heptan-3-one

: 134003-83-1
tert-butyl (1R,4R)-5-benzyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Guidance literature:: (1R,4R)-5-benzoyl-2,5-diazabicyclo[2.2.1]heptan-3-one; With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Reflux;

di-tert-butyl dicarbonate; With sodium hydroxide; In tetrahydrofuran;
DOI:10.1039/c4ra13611j