(1R,4R)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Base Information

Chemical Name:(1R,4R)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
CAS No.:134003-84-2
Molecular Formula:C10H18N2O2
Molecular Weight:198.265
Hs Code.:2933990090
European Community (EC) Number:800-374-2,849-889-4
Mol file:134003-84-2.mol

Synonyms:134003-84-2;(1R,4R)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate;TERT-BUTYL (1R,4R)-2,5-DIAZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE;1217975-73-9;(1R,4R)-rel-tert-Butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate;tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate hydrochloride;(1R,4R)-2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER;(1R,4R)-2-Boc-2,5-diazabicyclo[2.2.1]heptane;(1R,4R)-5-Boc-2,5-diazabicyclo[2.2.1]heptane;MFCD01321293;MFCD06411671;N-Boc-2,5-diaza-bicyclo[2.2.1]heptane;SCHEMBL1368037;UXAWXZDXVOYLII-HTQZYQBOSA-N;(1R,4R)-tert-Butyl2,5-diazabicyclo[2.2.1]heptane-2-carboxylate;AKOS006295610;AKOS015841284;DS-4518;N-Boc-2,5-diazabicyclo[2.2.1]heptane;EN300-269059;P10180;A806714;(R,R)-2-(tert-Butyloxycarbonyl)-2,5-diazabicyclo[2.2.1] heptane;(-)-2-(tert-butoxycarbonyl)-(1R, 4R)-2,5-diaza-bicyclo[2.2.1]heptane;(R,R)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester;1,1-dimethylethyl (1R,4R)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate;2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid,1,1-dimethylethyl ester;(1R,4R)-tert-Butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate, AldrichCPR;(R,R)-2,5-Diaza-bicyclo[2.2.1]heptane-2-c arboxylic acid tert-butyl ester

Suppliers and Price of (1R,4R)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1R,4R)-5-Boc-2,5-diazabicyclo[2.2.1]heptane
100mg
$ 45.00

Synthonix
tert-butyl(1R,4R)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate 97.0%
10g
$ 1000.00

SynQuest Laboratories
(1R,4R)-tert-Butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1 g
$ 698.00

SynQuest Laboratories
(1R,4R)-tert-Butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
250 mg
$ 295.00

Sigma-Aldrich
(1R,4R)-tert-Butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate Aldrich
100mg
$ 540.00

J&W Pharmlab
(1R,4R)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylicacidtert-butylester 97%
100mg
$ 117.00

J&W Pharmlab
(1R,4R)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylicacidtert-butylester 97%
250mg
$ 137.00

J&W Pharmlab
(1R,4R)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylicacidtert-butylester 97%
50mg
$ 98.00

J&W Pharmlab
(1R,4R)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylicacidtert-butylester 97%
1g
$ 248.00

J&W Pharmlab
(1R,4R)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylicacidtert-butylester 97%
500mg
$ 173.00

Total 38 raw suppliers

Chemical Property of (1R,4R)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Chemical Property:

Boiling Point:276.4±15.0 °C(Predicted)
PKA:9.74±0.20(Predicted)
PSA：41.57000
Density:1.104±0.06 g/cm3(Predicted)
LogP:1.23430
Storage Temp.:2-8°C
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:198.136827821
Heavy Atom Count:14
Complexity:247

Purity/Quality:

97% ^*data from raw suppliers

(1R,4R)-5-Boc-2,5-diazabicyclo[2.2.1]heptane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CC2CC1CN2
Isomeric SMILES:CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2
Uses (1R,4R)-5-Boc-2,5-diazabicyclo[2.2.1]heptane is a useful reagent employed in the preparation of tetrahydroisoquinolines as CXCR4 antagonists.

Technology Process of (1R,4R)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

There total 25 articles about (1R,4R)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

: 1134-94-7
2-phenylsulfanyl-aniline

: 1885-14-9
phenyl chloroformate

: 111974-73-3
phenyl [2-(phenylsulphanyl)phenyl]carbamate

Guidance literature:: 2-phenylsulfanyl-aniline; phenyl chloroformate; In toluene; at 4 ℃; for 0.0833333h;

phenyl chloroformate; With sodium carbonate; sodium hydroxide; In water; toluene; at 4 ℃; for 1.5h;