C₁₇H₁₃ClFNO₃S

Base Information

• Chemical Name: C₁₇H₁₃ClFNO₃S
• CAS No.: 1392201-09-0
• Molecular Formula: C₁₇H₁₃ClFNO₃S
• Molecular Weight: 365.813
• Mol file: 1392201-09-0.mol

Synonyms:

Chemical Property of C₁₇H₁₃ClFNO₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₃ClFNO₃S

There total 7 articles about C₁₇H₁₃ClFNO₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H13ClFNOS (1392201-04-5) → C17H13ClFNO3S (1392201-09-0)

Guidance literature:

With sodium tungstate (VI) dihydrate; dihydrogen peroxide; In acetic acid; at 30 ℃; for 6h;

DOI:10.3390/molecules17055870

Reference yield:

4-chloro-6-fluoro-2-methylquinoline 1-oxide (1392200-81-5) → C17H13ClFNO3S (1392201-09-0)

Guidance literature:

Multi-step reaction with 3 steps

1: benzenesulfonyl chloride / toluene / 3 h / 80 °C

2: potassium carbonate / acetonitrile / 2 h / 50 °C

3: sodium tungstate (VI) dihydrate; dihydrogen peroxide / acetic acid / 6 h / 30 °C

With sodium tungstate (VI) dihydrate; dihydrogen peroxide; potassium carbonate; benzenesulfonyl chloride; In acetic acid; toluene; acetonitrile;

DOI:10.3390/molecules17055870

Reference yield:

4-chloro-2-(chloromethyl)-6-fluoroquinoline (1392200-82-6) → C17H13ClFNO3S (1392201-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 2 h / 50 °C

2: sodium tungstate (VI) dihydrate; dihydrogen peroxide / acetic acid / 6 h / 30 °C

With sodium tungstate (VI) dihydrate; dihydrogen peroxide; potassium carbonate; In acetic acid; acetonitrile;

DOI:10.3390/molecules17055870

upstream raw materials:

4-chloro-6-fluoro-2-methylquinoline

4-chloro-6-fluoro-2-methylquinoline 1-oxide

4-chloro-2-(chloromethyl)-6-fluoroquinoline

C₁₇H₁₃ClFNOS

Downstream raw materials:

6-fluoro-2-(((4-methoxyphenyl)sulfonyl)methyl)-N-(3-morpholin-4ylpropyl)quinolin-4-amine