2-(5-(4-Methoxyphenyl)-1H-pyrazol-3-yl)acetonitrile

Base Information

Chemical Name:2-(5-(4-Methoxyphenyl)-1H-pyrazol-3-yl)acetonitrile
CAS No.:134161-75-4
Molecular Formula:C12H11N3O
Molecular Weight:213.239
Hs Code.:
ChEMBL ID:CHEMBL2435476
DSSTox Substance ID:DTXSID801247780
Nikkaji Number:J921.128D,J3.638.019E
Mol file:134161-75-4.mol

Synonyms:134161-75-4;2-(5-(4-Methoxyphenyl)-1H-pyrazol-3-yl)acetonitrile;5-(4-Methoxyphenyl)-1H-pyrazole-3-acetonitrile;[5-(4-Methoxy-phenyl)-1H-pyrazol-3-yl]-acetonitrile;CHEMBL2435476;DTXSID801247780

Suppliers and Price of 2-(5-(4-Methoxyphenyl)-1H-pyrazol-3-yl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(5-(4-Methoxyphenyl)-1H-pyrazol-3-yl)acetonitrile

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:213.090211983
Heavy Atom Count:16
Complexity:265

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NNC(=C2)CC#N

Technology Process of 2-(5-(4-Methoxyphenyl)-1H-pyrazol-3-yl)acetonitrile

There total 3 articles about 2-(5-(4-Methoxyphenyl)-1H-pyrazol-3-yl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 61380-86-7
6-(4-methoxyphenyl)-3-cyano-4-methylsulfanyl-2H-pyran-2-one

: 134161-75-4
<5-(4-methoxyphenyl)-1H-pyrazol-3-yl>acetonitrile

Guidance literature:: With hydrazine; In methanol; Reflux;
DOI:10.1016/j.tetlet.2014.01.095

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 134161-75-4
<5-(4-methoxyphenyl)-1H-pyrazol-3-yl>acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / dimethylformamide / 6 h / 28 - 30 °C

2: hydrazine hydrate / methanol / Heating

With potassium hydroxide; hydrazine hydrate; In methanol; N,N-dimethyl-formamide; 1: Cyclization / 2: Cyclization;

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 134161-75-4
<5-(4-methoxyphenyl)-1H-pyrazol-3-yl>acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / dimethylformamide / 6 h / 28 - 30 °C

2: hydrazine monohydrate / methanol / Heating

With potassium hydroxide; hydrazine hydrate; In methanol; N,N-dimethyl-formamide;