2-isonicotinoyl-N-phenylhydrazinecarboxamide

Base Information

• Chemical Name: 2-isonicotinoyl-N-phenylhydrazinecarboxamide
• CAS No.: 15152-50-8
• Molecular Formula: C₁₃H₁₂N₄O₂
• Molecular Weight: 256.264
• Mol file: 15152-50-8.mol

Synonyms:Semicarbazide,1-isonicotinoyl-4-phenyl- (8CI); NSC 11958

Chemical Property of 2-isonicotinoyl-N-phenylhydrazinecarboxamide

Chemical Property:

• Density: 1.329g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-isonicotinoyl-N-phenylhydrazinecarboxamide

There total 2 articles about 2-isonicotinoyl-N-phenylhydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isoniazid (54-85-3,7640-37-1) + phenyl isocyanate (103-71-9) → 1-isonicotinoyl-4-phenyl-3-semicarbazide (15152-50-8)

Guidance literature:

With benzene;

Reference yield:

→ 1-isonicotinoyl-4-phenyl-3-semicarbazide (15152-50-8)

Guidance literature:

Isonicotinsaeurehydrazid, Phenylharnstoff;

DOI:10.1021/jo01266a088

Reference yield:

1-isonicotinoyl-4-phenyl-3-semicarbazide (15152-50-8) → N-phenyl-5-(pyridin-4-yl)-1,3,4-oxadiazol-2-amine (1617-94-3)

Guidance literature:

With polyethylene glycol supported Burgess reagent; In tetrahydrofuran; for 0.0333333h; Yield given; Irradiation; microwave, 100 W, Pyrex tube;

DOI:10.1016/S0040-4039(99)00382-2

upstream raw materials:

isoniazid

phenyl isocyanate

Downstream raw materials:

N-phenyl-5-(pyridin-4-yl)-1,3,4-oxadiazol-2-amine