Technology Process of 1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one
There total 16 articles about 1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
manganese(IV) oxide;
In
dichloromethane;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/acs.joc.6b01052
- Guidance literature:
-
phenylacetylene;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.166667h;
Inert atmosphere;
ortho-bromobenzaldehyde;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
for 2h;
Inert atmosphere;
With
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
dimethyl sulfoxide;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1002/chem.201602064
- Guidance literature:
-
2-bromobenzoic acid chloride;
With
bis-triphenylphosphine-palladium(II) chloride; triethylamine;
In
tetrahydrofuran;
for 0.166667h;
With
copper(l) iodide;
In
tetrahydrofuran;
for 0.166667h;
phenylacetylene;
In
tetrahydrofuran;
at 20 ℃;
for 18h;
Sealed tube;
DOI:10.1002/ejoc.202100188
