1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one

Base Information

Chemical Name:1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one
CAS No.:134419-77-5
Molecular Formula:C15H9BrO
Molecular Weight:285.14
Hs Code.:
DSSTox Substance ID:DTXSID80567626
Nikkaji Number:J963.138K
Wikidata:Q82453564
Mol file:134419-77-5.mol

Synonyms:1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one;134419-77-5;DTXSID80567626

Suppliers and Price of 1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:283.98368
Heavy Atom Count:17
Complexity:329

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C#CC(=O)C2=CC=CC=C2Br

Technology Process of 1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one

There total 16 articles about 1-(2-Bromophenyl)-3-phenylprop-2-yn-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 134419-85-5
2-bromo-α-(phenylethynyl)-benzenemethanol

: 134419-77-5
1-(2-bromophenyl)-3-phenylprop-2-yn-1-one

Guidance literature:: With manganese(IV) oxide; In dichloromethane; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.joc.6b01052

Reference yield: 92.0%

: 536-74-3
phenylacetylene

: 6630-33-7
ortho-bromobenzaldehyde

: 134419-77-5
1-(2-bromophenyl)-3-phenylprop-2-yn-1-one

Guidance literature:: phenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h; Inert atmosphere;

ortho-bromobenzaldehyde; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2h; Inert atmosphere;

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1002/chem.201602064

Reference yield: 90.0%

: 7154-66-7
2-bromobenzoic acid chloride

: 536-74-3
phenylacetylene

: 134419-77-5
1-(2-bromophenyl)-3-phenylprop-2-yn-1-one

Guidance literature:: 2-bromobenzoic acid chloride; With bis-triphenylphosphine-palladium(II) chloride; triethylamine; In tetrahydrofuran; for 0.166667h;

With copper(l) iodide; In tetrahydrofuran; for 0.166667h;

phenylacetylene; In tetrahydrofuran; at 20 ℃; for 18h; Sealed tube;
DOI:10.1002/ejoc.202100188