(3R)-3-[[(R)-alpha-Methylbenzyl]benzylamino]butanoic acid methyl ester

Base Information

Chemical Name:(3R)-3-[[(R)-alpha-Methylbenzyl]benzylamino]butanoic acid methyl ester
CAS No.:134430-97-0
Molecular Formula:C20H25NO2
Molecular Weight:311.424
Hs Code.:
DSSTox Substance ID:DTXSID101171497
Nikkaji Number:J983.289K
Mol file:134430-97-0.mol

Synonyms:SCHEMBL17793376;DTXSID101171497;Methyl (3R)-3-[[(1R)-1-phenylethyl](phenylmethyl)amino]butanoate;(3R)-3-[[(R)-alpha-Methylbenzyl]benzylamino]butanoic acid methyl ester;134430-97-0

Suppliers and Price of (3R)-3-[[(R)-alpha-Methylbenzyl]benzylamino]butanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3R)-3-[[(R)-alpha-Methylbenzyl]benzylamino]butanoic acid methyl ester

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:311.188529040
Heavy Atom Count:23
Complexity:346

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC(=O)OC)N(CC1=CC=CC=C1)C(C)C2=CC=CC=C2
Isomeric SMILES:C[C@H](CC(=O)OC)N(CC1=CC=CC=C1)[C@H](C)C2=CC=CC=C2

Technology Process of (3R)-3-[[(R)-alpha-Methylbenzyl]benzylamino]butanoic acid methyl ester

There total 7 articles about (3R)-3-[[(R)-alpha-Methylbenzyl]benzylamino]butanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 623-43-8
crotonic acid methyl ester

: 38235-77-7
(R)-N-benzyl-1-phenylethylamine

: methyl (3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)butanoate

: 134430-97-0
methyl (3R,αR)-3-(N-benzyl-N-α-methylbenzylamino)butanoate

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;
DOI:10.1016/j.tetasy.2006.05.008

Reference yield: 75.0%

: 623-43-8
crotonic acid methyl ester

: 38235-77-7
(R)-N-benzyl-1-phenylethylamine

: 134430-97-0
methyl (3R,αR)-3-(N-benzyl-N-α-methylbenzylamino)butanoate

Guidance literature:: With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2h;

Reference yield:

: 623-43-8,4358-59-2,18707-60-3,130981-57-6
methyl crotonate

: 38235-77-7
(R)-N-benzyl-1-phenylethylamine

: 134430-97-0
methyl (3R,αR)-3-(N-benzyl-N-α-methylbenzylamino)butanoate

Guidance literature:: (R)-N-benzyl-1-phenylethylamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; Inert atmosphere;

methyl crotonate; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;
DOI:10.1021/jo302712f