Technology Process of [(2R,3R)-3-ethyl-2-methyloxiran-2-yl]methyl benzoate
There total 3 articles about [(2R,3R)-3-ethyl-2-methyloxiran-2-yl]methyl benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (-)-dimethyl D-tartrate; titanium tetraisopropoxide; tert-butylhydroperoxide / molecular sieves 4 Angstroem / CH2Cl2; decane / 4 h / -20 °C
2: 7.35 g / trimethylphosphite; triethylamine / CH2Cl2; decane / 1.5 h
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; Dimethyl D-tartrate; triethylamine; phosphorous acid trimethyl ester;
4 A molecular sieve;
In
decane; dichloromethane;
DOI:10.1021/jo0162890
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 80 percent / lithium aluminum hydride / diethyl ether / 2 h / 0 - 20 °C
2: (-)-dimethyl D-tartrate; titanium tetraisopropoxide; tert-butylhydroperoxide / molecular sieves 4 Angstroem / CH2Cl2; decane / 4 h / -20 °C
3: 7.35 g / trimethylphosphite; triethylamine / CH2Cl2; decane / 1.5 h
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; lithium aluminium tetrahydride; Dimethyl D-tartrate; triethylamine; phosphorous acid trimethyl ester;
4 A molecular sieve;
In
diethyl ether; decane; dichloromethane;
DOI:10.1021/jo0162890
- Guidance literature:
-
With
triethylamine; phosphorous acid trimethyl ester;
In
decane; dichloromethane;
for 1.5h;
DOI:10.1021/jo0162890
