Technology Process of tert-butyl 2-(2,6-difluorophenylamino)phenylcarbamate
There total 4 articles about tert-butyl 2-(2,6-difluorophenylamino)phenylcarbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 2 h / 45 °C / 3087.28 - 3604.44 Torr / Large scale reaction
2: tetrahydrofuran / 11.21 h / 20 - 30 °C / Large scale reaction
With
palladium 10% on activated carbon; hydrogen;
In
tetrahydrofuran;
DOI:10.1021/op100113j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium tert-amylate / tetrahydrofuran / 1.12 h / 0 - 10 °C / Large scale reaction
1.2: 3 h / 9 - 15 °C / Large scale reaction
2.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 2 h / 45 °C / 3087.28 - 3604.44 Torr / Large scale reaction
3.1: tetrahydrofuran / 11.21 h / 20 - 30 °C / Large scale reaction
With
palladium 10% on activated carbon; sodium tert-amylate; hydrogen;
In
tetrahydrofuran;
DOI:10.1021/op100113j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium tert-amylate / tetrahydrofuran / 1.12 h / 0 - 10 °C / Large scale reaction
1.2: 3 h / 9 - 15 °C / Large scale reaction
2.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 2 h / 45 °C / 3087.28 - 3604.44 Torr / Large scale reaction
3.1: tetrahydrofuran / 11.21 h / 20 - 30 °C / Large scale reaction
With
palladium 10% on activated carbon; sodium tert-amylate; hydrogen;
In
tetrahydrofuran;
DOI:10.1021/op100113j
