rac-2-amino-3-phenylpropanal diethyl acetal

Base Information

• Chemical Name: rac-2-amino-3-phenylpropanal diethyl acetal
• CAS No.: 52961-44-1
• Molecular Formula: C₁₃H₂₁NO₂
• Molecular Weight: 223.315
• Mol file: 52961-44-1.mol

Synonyms:

Chemical Property of rac-2-amino-3-phenylpropanal diethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-2-amino-3-phenylpropanal diethyl acetal

There total 1 articles about rac-2-amino-3-phenylpropanal diethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

ethanol (64-17-5) + ethyl 2-amino-3-phenylpropanoate hydrochloride (3182-93-2) → rac-2-amino-3-phenylpropanal diethyl acetal (52961-44-1)

Guidance literature:

With hydrogenchloride; sodium amalgam;

DOI:10.1002/hlca.19800630113

Reference yield:

rac-2-amino-3-phenylpropanal diethyl acetal (52961-44-1) → (Z)-5-benzyl-3-(1'-hydroxyethylidene)-4-pyrrolin-2-one

Guidance literature:

Multi-step reaction with 3 steps

1: 3.060 g / ethanol / 2 h / 0 °C

2: 733 mg / 2N HCl / tetrahydrofuran; H₂O / 2 h / 0 °C

3: 336.4 mg / 2n NaOH / diethyl ether; CH₂Cl₂; H₂O / 0.05 h

With hydrogenchloride; sodium hydroxide; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water;

DOI:10.1002/hlca.19800630113

Reference yield:

rac-2-amino-3-phenylpropanal diethyl acetal (52961-44-1) → rac-2-actoacetylamino-3-phenylpropanal (74450-64-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 3.060 g / ethanol / 2 h / 0 °C

2: 733 mg / 2N HCl / tetrahydrofuran; H₂O / 2 h / 0 °C

With hydrogenchloride; In tetrahydrofuran; ethanol; water;

DOI:10.1002/hlca.19800630113

upstream raw materials:

ethanol

ethyl 2-amino-3-phenylpropanoate hydrochloride

Downstream raw materials:

rac-2-actoacetylamino-3-phenylpropanal diethyl acetal

2-Formamido-3-phenylpropionaldehyd diethyl acetal

rac-2-actoacetylamino-3-phenylpropanal