3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester

Base Information

Chemical Name:3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester
CAS No.:134653-73-9
Molecular Formula:C₁₄H₁₃NO₃
Molecular Weight:243.262
Hs Code.:
DSSTox Substance ID:DTXSID80438261
Nikkaji Number:J418.040B
Wikidata:Q82253944
Mol file:134653-73-9.mol

Synonyms:134653-73-9;3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester;DTXSID80438261;6-Phenyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid ethyl ester

Suppliers and Price of 3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:243.08954328
Heavy Atom Count:18
Complexity:403

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=CNC(=CC1=O)C2=CC=CC=C2

Technology Process of 3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester

There total 2 articles about 3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-88-4
benzoyl chloride

: 134653-70-6
α-acetyl-α-(dimethylaminomethylene)acetic acid,ethyl ester

: 134653-73-9
ethyl 4-oxo-6-phenyl-1,4-dihydropyridine-3-carboxylate

Guidance literature:: With n-butyllithium; ammonium acetate; acetic acid; 1,1,1,3,3,3-hexamethyl-disilazane; Yield given. Multistep reaction; 1. THF, hexanes, -70 deg C 2. 1.5 h, 60-65 deg C;
DOI:10.1021/jo00016a028

Reference yield:

: 57905-32-5
ethyl 2-(aminomethylene)-3-oxobutanoate

: 93-89-0,99341-95-4
benzoic acid ethyl ester

: 134653-73-9
ethyl 4-oxo-6-phenyl-1,4-dihydropyridine-3-carboxylate

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) THF, from -18 to -10 deg C, 2.) THF, reflux, 1 h;
DOI:10.1248/cpb.43.450