Technology Process of 4-(1,1,1,1,1-pentacarbonyl-1-chroma)-1,2,6-triphenyl-1,4-dihydropyrimidine
There total 1 articles about 4-(1,1,1,1,1-pentacarbonyl-1-chroma)-1,2,6-triphenyl-1,4-dihydropyrimidine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
dichloromethane;
soln. of Cr complex and N-phenyl-benzamidine in dry CH2Cl2 stirred at ambient temp.; volatiles removed under reduced pressure; purified by flash column chromy. (silica gel, hexanes/CH2Cl2 (1/1)); elem. anal.;
DOI:10.1016/j.jorganchem.2006.05.021
- Guidance literature:
-
In
tetrahydrofuran;
under N2; Cr complex and NaBH4 (1 equiv.) added to THF; stirred at ambient temp. for 5 h; volatiles removed under reduced pressure; purified by flash column chromy. (silica gel, hexanes/CH2Cl2 (1/1)); elem. anal.;
DOI:10.1016/j.jorganchem.2006.05.021
- Guidance literature:
-
With
sodium borohydride;
In
ethanol;
under N2; powdered sulfur and NaBH4 (molar ratio 1:1) added to EtOH; stirred at ambient temp. for 1 h; Cr complex (0.5 equiv.) added; stirred for 1 h; volatiles removed under reduced pressure; purified by flash column chromy. (silica gel, hexanes/CH2Cl2 (1/1)); elem. anal.;
DOI:10.1016/j.jorganchem.2006.05.021
