H-Leu-Tyr-Arg-Ala-Arg-NHNH₂

Base Information

• Chemical Name: H-Leu-Tyr-Arg-Ala-Arg-NHNH₂
• CAS No.: 1334711-13-5
• Molecular Formula: C₃₀H₅₃N₁₃O₆
• Molecular Weight: 691.834
• Mol file: 1334711-13-5.mol

Synonyms:

Chemical Property of H-Leu-Tyr-Arg-Ala-Arg-NHNH₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of H-Leu-Tyr-Arg-Ala-Arg-NHNH₂

There total 1 articles about H-Leu-Tyr-Arg-Ala-Arg-NHNH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Leu-OH (35661-60-0) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (35661-39-3,136132-75-7) → H-Leu-Tyr-Arg-Ala-Arg-NHNH2 (1334711-13-5)

Guidance literature:

Fmoc-Leu-OH; With HCTU; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; for 1h;

With piperidine; In N,N-dimethyl-formamide; for 0.2h;

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Fmoc-Tyr(Pg)-OH; Fmoc-Arg(Pg)-OH; Further stages;

DOI:10.1039/c8ob01810c

Reference yield:

H-Leu-Tyr-Arg-Ala-Arg-NHNH2 (1334711-13-5) → C30H50N14O6

Guidance literature:

With sodium nitrite; In water; at -10 ℃; for 0.333333h;

DOI:10.1039/c8cc03591a

Reference yield:

H-Leu-Tyr-Arg-Ala-Arg-NHNH2 (1334711-13-5) + methyl (E)-3-(3-chloro-4-formylphenyl)acrylate → C41H60ClN13O8

Guidance literature:

In ethanol; at 25 ℃; for 0.5h; pH=7;

DOI:10.1039/c8ob01810c

upstream raw materials:

Fmoc-Leu-OH

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Downstream raw materials:

C₅₉H₉₃N₁₉O₁₃S₂