4-nitrobenzaldehyde N-benzylhydrazone

Base Information

• Chemical Name: 4-nitrobenzaldehyde N-benzylhydrazone
• CAS No.: 104707-43-9
• Molecular Formula: C₁₄H₁₃N₃O₂
• Molecular Weight: 255.276
• Mol file: 104707-43-9.mol

Synonyms:

Chemical Property of 4-nitrobenzaldehyde N-benzylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-nitrobenzaldehyde N-benzylhydrazone

There total 3 articles about 4-nitrobenzaldehyde N-benzylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitrobenzaldehdye (555-16-8) + Benzylhydrazine (555-96-4) → 4-nitrobenzaldehyde N-benzylhydrazone (104707-43-9)

Guidance literature:

DOI:10.1007/BF02901158

Reference yield:

N-[(1,1-dimethylethyl)diphenylsilyl]benzenemethanamine (119645-09-9) → 4-nitrobenzaldehyde N-benzylhydrazone (104707-43-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tert-butylhypochlorite / chloroform / 3 h / 0 °C / Inert atmosphere

1.2: 18 h / 0 - 20 °C / Inert atmosphere

2.1: 3-chloro-benzenecarboperoxoic acid; potassium hydroxide / dichloromethane / 1.5 h / 0 °C / Inert atmosphere

3.1: acetonitrile / 20 °C

With tert-butylhypochlorite; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; In dichloromethane; chloroform; acetonitrile;

DOI:10.1021/jo302182t

Reference yield:

N-[(1,1-dimethylethyl)diphenylsilyl]-4-nitrobenzaldimine (1413917-19-7) → 4-nitrobenzaldehyde N-benzylhydrazone (104707-43-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid; potassium hydroxide / dichloromethane / 1.5 h / 0 °C / Inert atmosphere

2: acetonitrile / 20 °C

With 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; In dichloromethane; acetonitrile;

DOI:10.1021/jo302182t

upstream raw materials:

4-nitrobenzaldehdye

Benzylhydrazine

N-[(1,1-dimethylethyl)diphenylsilyl]benzenemethanamine

N-[(1,1-dimethylethyl)diphenylsilyl]-4-nitrobenzaldimine

Downstream raw materials:

2-Benzyl-5-(4-nitro-phenyl)-4-phenyl-2,4-dihydro-[1,2,4]triazol-3-one

2-benzyl-5-(4′-nitrophenyl)tetrazole

C₂₁H₁₈N₄O₃

Refernces

• 1、 Richy, Nicolas,Ghoraf, Mohammed,Vidal, Jo?lle. "N-silyloxaziridines: Synthesis and use for electrophilic amination". . p. 10972 - 10977. Retrieved 2013/02/22.