Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid

Base Information

• Chemical Name: Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid
• CAS No.: 85726-82-5
• Molecular Formula: C₂₈H₃₀Br₂O₁₀
• Molecular Weight: 686.348
• Mol file: 85726-82-5.mol

Synonyms:

Chemical Property of Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid

There total 7 articles about Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

Methyl-4-O-benzoyl-2-brom-2,6-didesoxy-β-D-glucopyranosid (85726-79-0) + 4-O-Benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-clucopyranosylbromid (85726-77-8) → 1,5-Anhydro-4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-D-arabino-hex-1-enit (85726-83-6) + Methyl-3-O-acetyl-4-O-benzoyl-2-brom-2,6-didesoxy-β-D-glucopyranosid (85726-80-3) + Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-β-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid (85726-81-4) + Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid (85726-82-5)

Guidance literature:

With silver (II) carbonate; In dichloromethane; for 96h; Ambient temperature;

Reference yield:

Methyl 4,6-O-benzylidene-2,3-O-isopropylidene-α-D-mannopyranoside (85761-43-9) → Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid (85726-82-5)

Guidance literature:

Multi-step reaction with 6 steps

1: 86 percent / N-bromsuccinimide, BaCO₃ / CCl₄ / 0.5 h / Heating

2: 83 percent / Na-borate / Ni(II)-chlorid-hexahydrate / ethanol / Ambient temperature

3: 89 percent / (dibrommethyl)methylether / ZnBr / CH₂Cl₂ / 12 h / Ambient temperature

4: 79 percent / AgCO₃ / diethyl ether / 8 h / Ambient temperature

5: 80 percent / conc. HCl / methanol / 4 h / Heating

6: 5 percent / AgCO₃ / CH₂Cl₂ / 96 h / Ambient temperature

With hydrogenchloride; silver (II) carbonate; N-Bromosuccinimide; α,α-dibromomethyl methyl ether; Na-borate; barium carbonate; nickel dichloride; zinc dibromide; In methanol; tetrachloromethane; diethyl ether; ethanol; dichloromethane;

Reference yield:

Methyl-4-O-benzoyl-6-brom-6-desoxy-2,3-O-isopropyliden-α-D-mannopyranosid (85726-75-6) → Methyl-4-O-benzoyl-3-O-(4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-glucopyranosyl)-2-brom-2,6-didesoxy-β-D-glucopyranosid (85726-82-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 83 percent / Na-borate / Ni(II)-chlorid-hexahydrate / ethanol / Ambient temperature

2: 89 percent / (dibrommethyl)methylether / ZnBr / CH₂Cl₂ / 12 h / Ambient temperature

3: 79 percent / AgCO₃ / diethyl ether / 8 h / Ambient temperature

4: 80 percent / conc. HCl / methanol / 4 h / Heating

5: 5 percent / AgCO₃ / CH₂Cl₂ / 96 h / Ambient temperature

With hydrogenchloride; silver (II) carbonate; α,α-dibromomethyl methyl ether; Na-borate; nickel dichloride; zinc dibromide; In methanol; diethyl ether; ethanol; dichloromethane;

upstream raw materials:

Methyl-4-O-benzoyl-2-brom-2,6-didesoxy-β-D-glucopyranosid

4-O-Benzoyl-2-brom-2,6-didesoxy-3-O-formyl-α-D-clucopyranosylbromid

Methyl 4,6-O-benzylidene-2,3-O-isopropylidene-α-D-mannopyranoside

Methyl-4-O-benzoyl-2-brom-2,6-didesoxy-3-O-formyl-β-D-glucopyranosid

Downstream raw materials:

Methyl-4-O-benzoyl-2,6-didesoxy-3-O-(3,4-di-O-acetyl-2,6-didesoxy-α-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosid