Technology Process of 2-oxo-3,3-diphenyl-cyclopentanecarbaldehyde
There total 4 articles about 2-oxo-3,3-diphenyl-cyclopentanecarbaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 85 percent / H2SO4; hydrogen peroxide / acetic acid / 1 h / 20 °C
2: sodium hydride; methanol / tetrahydrofuran / 16 h / 0 - 20 °C
With
methanol; sulfuric acid; dihydrogen peroxide; sodium hydride;
In
tetrahydrofuran; acetic acid;
1: Rearrangement / 2: Formylation;
DOI:10.1021/jo000095n
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 74 percent / p-toluenesulfonic acid / benzene / 3 h / Heating
2: 85 percent / H2SO4; hydrogen peroxide / acetic acid / 1 h / 20 °C
3: sodium hydride; methanol / tetrahydrofuran / 16 h / 0 - 20 °C
With
methanol; sulfuric acid; dihydrogen peroxide; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; acetic acid; benzene;
1: Dehydration / 2: Rearrangement / 3: Formylation;
DOI:10.1021/jo000095n
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 12 h / 20 °C
2: 74 percent / p-toluenesulfonic acid / benzene / 3 h / Heating
3: 85 percent / H2SO4; hydrogen peroxide / acetic acid / 1 h / 20 °C
4: sodium hydride; methanol / tetrahydrofuran / 16 h / 0 - 20 °C
With
methanol; sulfuric acid; dihydrogen peroxide; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; acetic acid; benzene;
1: Grignard reaction / 2: Dehydration / 3: Rearrangement / 4: Formylation;
DOI:10.1021/jo000095n
