2-Chloro-N-ethylbenzenamine

Base Information

• Chemical Name: 2-Chloro-N-ethylbenzenamine
• CAS No.: 13519-74-9
• Molecular Formula: C8H10ClN
• Molecular Weight: 155.627
• Hs Code.: 2921420090
• Mol file: 13519-74-9.mol

Synonyms:Benzenamine, 2-chloro-N-ethyl-;Aniline,o-chloro-N-ethyl;o-chloro-N-ethylaniline;2-chloro-N-ethyl-benzenamine;N-ethyl-2-chloro-aniline;N-Aethyl-2-chlor-anilin;Benzenamine,2-chloro-N-ethyl;

Chemical Property of 2-Chloro-N-ethylbenzenamine

Chemical Property:

• PSA: 12.03000
• LogP: 2.84480

Purity/Quality:

99% ^*data from raw suppliers

Benzenamine,2-chloro-N-ethyl- 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chloro-N-ethylbenzenamine

There total 16 articles about 2-Chloro-N-ethylbenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N-(2-chlorophenyl)acetamide (533-17-5) → o-chloro-N-ethylaniline (13519-74-9)

Guidance literature:

With dimethylsulfide borane complex; In 2-methyltetrahydrofuran; at 90 ℃; for 0.333333h; under 7500.75 Torr; chemoselective reaction; Inert atmosphere; Flow reactor;

DOI:10.1002/cssc.201903459

Reference yield: 79.0%

triethylamine (121-44-8) + o-chloroaniline (95-51-2) → o-chloro-N-ethylaniline (13519-74-9)

Guidance literature:

With [(phenylbenzothiazole)₂Ir(nBu)₃]OTf; In 5,5-dimethyl-1,3-cyclohexadiene; at 155 ℃; for 10h; Inert atmosphere; Schlenk technique;

Reference yield: 73.0%

N-(2-chlorophenyl)acetamide (533-17-5) → o-chloro-N-ethylaniline (13519-74-9) + o-chloroaniline (95-51-2)

Guidance literature:

With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); formic acid; bis(trifluoromethanesulfonyl)amide; triethylamine; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine]; In dibutyl ether; at 130 ℃; for 24h;

DOI:10.1002/adsc.201900406

upstream raw materials:

N-ethyl-2-chloro-N-nitroso-aniline

N-(2-chloro-phenyl)-alanine

diethyl sulfate

o-chloroaniline

Downstream raw materials:

N-(2-chlorophenyl)-N-ethylethenesulfonamide

N-(2-chlorophenyl)pyridin-2-amine

2-(o-chloro-N-ethylanilino)pyridine

C₁₉H₁₇ClN₂O₄