533-17-5

Basic information

• Product Name: 2'-Chloroacetanilide
• Synonyms: o-Chloracetanilide;o-Chloroacetanilide;2'-CHLOROACETANILIDE;2-CHLOROACETANILIDE;2-Chloroacetanilide, 98+%;2'-Chloroacetanilide, 99+%;AVO 2-Chloroacetanilide;Acetanilide, 2'-chloro- (8CI)
• CAS NO: 533-17-5
• Molecular Formula: C₈H₈ClNO
• Molecular Weight: 169.61
• EINECS: 208-555-2
• Product Categories: Anilines, Amides & Amines;Chlorine Compounds;Nitrogen Compounds;Organic Building Blocks;Protected Amines
• Mol File: 533-17-5.mol
• Article Data: 115

Chemical Properties

• Melting Point: 88-90 °C(lit.)
• Boiling Point: 306.5°C (rough estimate)
• Flash Point: 150.5 °C
• Appearance: beige to light brown crystalline powder
• Density: 1.1885 (rough estimate)
• Refractive Index: 1.5430 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.19±0.70(Predicted)
• Water Solubility: practically insoluble
• Merck: 14,2111
• BRN: 2086967
• CAS DataBase Reference: 2'-Chloroacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-Chloroacetanilide(533-17-5)
• EPA Substance Registry System: 2'-Chloroacetanilide(533-17-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 533-17-5(Hazardous Substances Data)

Usage

Chemical Properties

SLIGHTLY BEIGE CRYSTALLINE POWDER

Uses

2''-Chloroacetanilide

Upstream product

• 579-11-3 N-chloroacetanilide 
• 64-19-7 acetic acid 
• 95-51-2 o-chloroaniline 
• 552-16-9 ortho-nitrobenzoic acid 
• 108-90-7 chlorobenzene 
• 121-92-6 3-nitrobenzoic acid 
• 625-77-4 N-acetylacetamide 
• 473-34-7 N,N-dichloro-p-toluenesulfonamide 
• 103-84-4 Acetanilid 
• 2959-01-5 N,N'-dichloro-urea 
• 56-23-5 tetrachloromethane 
• 94-36-0 dibenzoyl peroxide 
• 1795-83-1 N-Phenylacetohydroxamic acid 
• 91631-52-6 N-sulfonoxyacetanilide pyridinium salt 

Downstream Products

• 65256-76-0 4,4'-diamino-3,3'-dichloro-benzophenone 
• 102677-67-8 N-(3-Acetylamino-4-chloro-benzyl)-2-chloro-acetamide 
• 74407-98-0 N,N-dimethyl-N'-(2-chlorophenyl)formamidine 
• 207992-40-3 N-allyl-N-(2-chloro-phenyl)-acetamide 
• 74585-36-7 N-benzyl-o-chloroacetanilide 
• 42822-64-0 [2-(N-acetyl)aminophenyl]phosphonic acid diethyl ester 
• 56074-07-8 4-acetamido-3-chlorophenol 
• 935742-43-1 N-(2-methylprop-2-enyl)-N-o-chlorophenylacetamide 
• 68874-08-8 2-methyl-1-(4-methylphenyl)-1H-benzimidazole 
• 754211-10-4 5-chloro-N-(2-chlorophenyl)-6-methylpyrazolo[1,5-a]pyrimidin-7-amine 
• 64-17-5 ethanol 
• 95-51-2 o-chloroaniline 
• 49747-46-8 N-(2-chlorophenyl)-4-methylbenzamide 
• 1020-39-9 N-(2-chlorophenyI)benzamide 

Relevant articles and documents

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Preparation and catalytic evaluation of a palladium catalyst deposited over modified clinoptilolite (Pd&at;MCP) for chemoselective N-formylation and N-acylation of amines

Novel palladium nanoparticles stabilized by clinoptilolite as a natural inexpensive zeolite prepared and used for N-formylation and N-acylation of amines at room temperature at environmentally benign reaction conditions in good to excellent yields. Pd (II) was immobilized on the surface of clinoptilolite via facile multi-step amine functionalization to obtain a sustainable, recoverable, and highly active nano-catalyst. The structural and morphological characterizations of the catalyst carried out using XRD, FT-IR, BET and TEM techniques. Moreover, the catalyst is easily recovered using simple filtration and reused for 7 consecutive runs without any loss in activity.

Method for catalyzing one-pot hydrogenation and amidation of nitroaromatic hydrocarbon and carboxylic acid by visible light

The invention discloses a method for catalyzing one-pot hydrogenation and amidation reaction of nitroaromatic hydrocarbon and carboxylic acid by visible light. The method comprises the following steps: preparing Pt nanoparticles uniformly dispersed on an N-doped titanium dioxide/titanium carbide (MXene) heterojunction as a photocatalyst (3% Pt/N-TiO2/Ti3C2), and applying the catalyst to a cascade reaction of an aromatic nitro compound and carboxylic acid to prepare an amide product. The 3% Pt/N-TiO2/Ti3C2 has excellent tandem hydrogenation and amidation activity and chemical selectivity of an aromatic nitro compound and carboxylic acid under the irradiation of visible light. The excellent catalytic performance of 3% Pt/N-TiO2/Ti3C2 is attributed to the close contact of TiO2 and conductive Ti3C2, and the separation efficiency of photo-induced electrons and holes is improved through charge short-range directional transmission. The preparation method of the catalyst is simple and easy to operate, the catalyst can be used for photocatalytic efficient one-pot hydrogenation and amidation reactions, the reaction conditions are mild, and the catalyst is easy to recycle.