4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole

Base Information

• Chemical Name: 4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole
• CAS No.: 1038692-16-8
• Molecular Formula: C₂₅H₁₅F₅N₄
• Molecular Weight: 466.413
• Mol file: 1038692-16-8.mol

Synonyms:

Chemical Property of 4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole

There total 1 articles about 4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

perfluorobenzaldehyde (653-37-2) + N,N'-dibenzyldiaminomaleonitrile (51802-04-1) → 4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole (1038692-16-8)

Guidance literature:

In acetic acid; at 20 ℃; for 48h;

DOI:10.1016/j.jorganchem.2008.01.039

Reference yield: 43.0%

4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole (1038692-16-8) + carbonylchloro(1,3-dibenzyl-4,5-dicyano-1H-imidazolin-2-ylidene)rhodium(I) dimer → trans-carbonylchlorobis(1,3-dibenzyl-4,5-dicyano-1H-imidazolin-2-ylidene)rhodium(I)

Guidance literature:

In 1,3,5-trimethyl-benzene; (N2); addn. of 1 equiv. of (RhCl(CO)(C3(CN)2N2(CH2C6H5)2))2 to 2 equiv. of 4,5-dicyano-1,3-dibenzyl-2-pentafluorophenyl-2,3-dihydroimidazole in mesitylene at 165°C; stirring for 6 h; removal of solvent in vac., chromy. using silica as stationary phase andCH2Cl2 as eluent; drying under reduced pressure; elem. anal.;

DOI:10.1021/om900785p

Reference yield:

4,5-dicyano-1,3-dibenzyl-2-(pentafluorophenyl)-2,3-dihydroimidazole (1038692-16-8) + carbonylchloro(1,3-dibenzyl-4,5-dichloro-1H-imidazolin-2-ylidene)rhodium(I) dimer → trans-carbonylchlorobis(1,3-dibenzyl-4,5-dichloro-1H-imidazolin-2-ylidene)rhodium(I) + trans-carbonylchloro-1,3-dibenzyl-4,5-dichloro-1H-imidazolin-2-ylidene-1,3-dibenzyl-4,5-dicyano-1H-imidazolin-2-ylidenerhodium(I)

Guidance literature:

In 1,3,5-trimethyl-benzene; (N2); addn. of 1 equiv. of (RhCl(CO)(C3Cl2N2(CH2C6H5)2))2 to 2 equiv. of4,5-dicyano-1,3-dibenzyl-2-pentafluorophenyl-2,3-dihydroimidazole in me sitylene at 165°C; stirring for 6 h; removal of solvent in vac., chromy. using silica as stationary phase andCH2Cl2 as eluent; drying under reduced pressure; as mixt.;

DOI:10.1021/om900785p

upstream raw materials:

perfluorobenzaldehyde

N,N'-dibenzyldiaminomaleonitrile