1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole

Base Information

• Chemical Name: 1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole
• CAS No.: 1299472-03-9
• Molecular Formula: C₂₃H₃₀OSn
• Molecular Weight: 441.201
• Mol file: 1299472-03-9.mol

Synonyms:

Chemical Property of 1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole

There total 5 articles about 1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

dineophyltin dihydride (1299471-99-0) + propargyl alcohol (107-19-7) → 1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole (1299472-03-9) + (2Z,2E')-(HOCH2CHCH)2Sn(CH2CMe2Ph)2 (1299472-04-0,1299472-05-1) + (2E,2E')-(HOCH2CHCH)2Sn(CH2CMe2Ph)2 (1299472-04-0,1299472-05-1)

Guidance literature:

With azobisisobutyronitrile; In neat (no solvent); HOCH2CCH (4.52 mmol) treated with Neoph2SnH2 (1.81 mmol) and AIBN (0.01 equiv.) under N2 at 80°C for 5 min; chromd. (silica gel 60; hexane/Et2O (97:3)); ratio of (OCH2CHCH)SnNeoph2/(2Z,2E')-(HOCH2CHCH)2SnNeoph2/(2E,2E')-(HOCH2CHCH)2SnNeoph2=52:31:17, elem. anal.;

DOI:10.1016/j.jorganchem.2010.12.033

Reference yield:

2-methyl-2-phenyl-1-propylmagnesium chloride (35293-35-7) → 1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole (1299472-03-9) + (2Z,2E')-(HOCH2CHCH)2Sn(CH2CMe2Ph)2 (1299472-04-0,1299472-05-1) + (2E,2E')-(HOCH2CHCH)2Sn(CH2CMe2Ph)2 (1299472-04-0,1299472-05-1)

Guidance literature:

Multi-step reaction with 4 steps

1: diethyl ether

2: tetrachloromethane

3: diethyl ether

4: azobisisobutyronitrile / neat (no solvent)

With azobisisobutyronitrile; In tetrachloromethane; diethyl ether;

DOI:10.1016/j.jorganchem.2010.12.033

Reference yield:

dineophyltin dichloride (14208-42-5) → 1,1-dineophyl-2,3-dihydro-3-methyl-2-oxastannole (1299472-03-9) + (2Z,2E')-(HOCH2CHCH)2Sn(CH2CMe2Ph)2 (1299472-04-0,1299472-05-1) + (2E,2E')-(HOCH2CHCH)2Sn(CH2CMe2Ph)2 (1299472-04-0,1299472-05-1)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: azobisisobutyronitrile / neat (no solvent)

With azobisisobutyronitrile; In diethyl ether;

DOI:10.1016/j.jorganchem.2010.12.033

upstream raw materials:

2-methyl-2-phenyl-1-propylmagnesium chloride

dineophyltin dihydride

propargyl alcohol

dineophyltin dichloride