(αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid

Base Information

Chemical Name:(αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid
CAS No.:98153-41-4
Molecular Formula:C₁₅H₁₆ClNO₃S
Molecular Weight:325.816
Hs Code.:

Synonyms:

Suppliers and Price of (αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid

There total 5 articles about (αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 98153-39-0
benzhydryl (αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanate

: 98153-41-4
(αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid

Guidance literature:: With 2,2,2-trifluoroethanol; trifluoroacetic acid; at 0 ℃; for 2h;

Reference yield:

: 75527-84-3
diphenylmethyl 6,6-dibromopenicillanate

: 98153-41-4
(αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) methylmagnesium bromide / 1.) THF, diethyl ether, -70 deg C, 15 min, 2.) -70 deg C, 15 min

2: 57 percent / tributyltin hydride, azoisobutyronitrile / benzene / 2 h / Heating

3: 97 percent / N-chlorosuccinimide, triphenylphosphine / tetrahydrofuran / 1.5 h / Ambient temperature

4: 52 percent / trifluoroethanol, trifluoroacetic acid / 2 h / 0 °C

With N-chloro-succinimide; 2,2'-azobis(isobutyronitrile); 2,2,2-trifluoroethanol; methylmagnesium bromide; tri-n-butyl-tin hydride; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; benzene;

Reference yield:

: 100-52-7
benzaldehyde

: 98153-41-4
(αS,3S,5R,6R)-6-(α-chlorobenzyl)penicillanic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) methylmagnesium bromide / 1.) THF, diethyl ether, -70 deg C, 15 min, 2.) -70 deg C, 15 min

2: 57 percent / tributyltin hydride, azoisobutyronitrile / benzene / 2 h / Heating

3: 97 percent / N-chlorosuccinimide, triphenylphosphine / tetrahydrofuran / 1.5 h / Ambient temperature

4: 52 percent / trifluoroethanol, trifluoroacetic acid / 2 h / 0 °C

With N-chloro-succinimide; 2,2'-azobis(isobutyronitrile); 2,2,2-trifluoroethanol; methylmagnesium bromide; tri-n-butyl-tin hydride; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; benzene;