N--Ala-O-(Z-TF)-Ser-OCH3

Base Information

• Chemical Name: N--Ala-O-(Z-TF)-Ser-OCH3
• CAS No.: 17896-59-2
• Molecular Formula: C₂₄H₂₅ClF₃N₃O₇
• Molecular Weight: 559.927
• Mol file: 17896-59-2.mol

Synonyms:

Chemical Property of N--Ala-O-(Z-TF)-Ser-OCH3

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N--Ala-O-(Z-TF)-Ser-OCH3

There total 3 articles about N--Ala-O-(Z-TF)-Ser-OCH3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(p-chlorobenzoyl)-L-alanine (63013-10-5) → N--Ala-O-(Z-TF)-Ser-OCH3 (17896-59-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) DCC, N-hydroxysuccinimide, THF, (ii) /BRN= 3559591/, Et₃N

2: Et₃N / tetrahydrofuran

With triethylamine; In tetrahydrofuran;

DOI:10.1002/cber.19681010323

Reference yield:

4-chloro-benzoyl chloride (122-01-0) → N--Ala-O-(Z-TF)-Ser-OCH3 (17896-59-2)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. NaOH

2: (i) DCC, N-hydroxysuccinimide, THF, (ii) /BRN= 3559591/, Et₃N

3: Et₃N / tetrahydrofuran

With sodium hydroxide; triethylamine; In tetrahydrofuran;

DOI:10.1002/cber.19681010323

Reference yield:

2,2,2-Trifluor-1-chlor-N-benzyloxycarbonyl-ethylamin + Bz(Cl)-Ala-Ser-OCH3 (17896-58-1) → N--Ala-O-(Z-TF)-Ser-OCH3 (17896-59-2)

Guidance literature:

With triethylamine; In tetrahydrofuran;

DOI:10.1002/cber.19681010323

upstream raw materials:

Bz(Cl)-Ala-Ser-OCH₃

N-(p-chlorobenzoyl)-L-alanine

4-chloro-benzoyl chloride