3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid

Base Information

Chemical Name:3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid
CAS No.:765937-82-4
Molecular Formula:C₁₃H₉NO₅
Molecular Weight:259.218
Hs Code.:
European Community (EC) Number:621-268-0
DSSTox Substance ID:DTXSID801213230

Synonyms:3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid;58110-36-4;765937-82-4;3-(5-(2-NITROPHENYL)FURAN-2-YL)ACRYLIC;(2E)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-enoic acid;(2e)-3-[5-(2-nitrophenyl)-2-furyl]acrylic acid;3-[5-(2-Nitro-phenyl)-furan-2-yl]-acrylic acid;(E)-3-(5-(2-nitrophenyl)furan-2-yl)acrylic acid;SCHEMBL5032492;(E)-3-[5-(2-nitrophenyl)furan-2-yl]prop-2-enoic acid;DTXSID801213230;BBL012318;MFCD00551680;STK803171;AKOS000109217;BB 0245554;CS-0322888;3-(5-(2-Nitrophenyl)furan-2-yl)acrylicacid;3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid, 97%;(E)-3-[5-(2-Nitro-phenyl)-furan-2-yl]-acrylic acid;(e)-3-[5-(2-nitro-phenyl)-furan-2-yl]-acrylic acid;(2E)-3-[5-(2-Nitrophenyl)-2-furanyl]-2-propenoic acid

Suppliers and Price of 3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:259.04807239
Heavy Atom Count:19
Complexity:376

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CC=C(O2)C=CC(=O)O)[N+](=O)[O-]
Isomeric SMILES:C1=CC=C(C(=C1)C2=CC=C(O2)/C=C/C(=O)O)[N+](=O)[O-]

Technology Process of 3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid

There total 2 articles about 3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 141-82-2
malonic acid

: 20000-96-8
5-(2-nitrophenyl)-2-furaldehyde

: 765937-82-4
3-[5-(2-nitrophenyl)-2-furyl]acrylic acid

Guidance literature:: With piperidine; pyridine; for 2h; Heating;
DOI:10.1016/j.bmc.2004.07.010

Reference yield:

: 5570-19-4
2-nitrophenylboronic acid

: 765937-82-4
3-[5-(2-nitrophenyl)-2-furyl]acrylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (Ph₃P)4Pd; aq. K₂CO₃ / toluene; ethanol / 5 h / Heating

2: pyridine; piperidine / 2 h / Heating

With piperidine; pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; toluene; 1: Suzuki coupling;
DOI:10.1016/S0960-894X(02)00555-3