Ethyl [2-(4-bromophenyl)ethyl]carbamate

Base Information

Chemical Name:Ethyl [2-(4-bromophenyl)ethyl]carbamate
CAS No.:135335-11-4
Molecular Formula:C11H14BrNO2
Molecular Weight:272.142
Hs Code.:
DSSTox Substance ID:DTXSID60569522
Nikkaji Number:J2.886.444B
Wikidata:Q82456681
Mol file:135335-11-4.mol

Synonyms:135335-11-4;Ethyl [2-(4-bromophenyl)ethyl]carbamate;SCHEMBL159731;DTXSID60569522;FTHSGSVYIKGLIG-UHFFFAOYSA-N;[2-(4-bromo-phenyl)-ethyl]-carbamic acid ethyl ester

Suppliers and Price of Ethyl [2-(4-bromophenyl)ethyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Ethyl [2-(4-bromophenyl)ethyl]carbamate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:271.02079
Heavy Atom Count:15
Complexity:191

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NCCC1=CC=C(C=C1)Br

Technology Process of Ethyl [2-(4-bromophenyl)ethyl]carbamate

There total 3 articles about Ethyl [2-(4-bromophenyl)ethyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 73918-56-6
4-Bromophenethylamine

: 541-41-3
chloroformic acid ethyl ester

: 135335-11-4
ethyl <2-(4-bromophenyl)ethyl>carbamate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/jm00086a004

Reference yield: 81.5%

: 135335-11-4
ethyl <2-(4-bromophenyl)ethyl>carbamate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 3h; Cooling with ice;

Reference yield:

: 16532-79-9
4-Bromophenylacetonitrile

: 135335-11-4
ethyl <2-(4-bromophenyl)ethyl>carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: borane-THF / tetrahydrofuran / 24.5 h / 0 °C / Reflux

1.2: 4 h / Reflux

2.1: triethylamine / dichloromethane / 3 h / 0 - 20 °C

With borane-THF; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2018.07.048