benzyl 2-hydroxy-2-methylbutanoate

Base Information

• Chemical Name: benzyl 2-hydroxy-2-methylbutanoate
• CAS No.: 54086-29-2
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• Mol file: 54086-29-2.mol

Synonyms:

Chemical Property of benzyl 2-hydroxy-2-methylbutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 2-hydroxy-2-methylbutanoate

There total 2 articles about benzyl 2-hydroxy-2-methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

benzyl tiglate (37526-88-8) → benzyl 2-hydroxy-2-methylbutanoate (54086-29-2,131375-82-1)

Guidance literature:

With phenylsilane; oxygen; bis(dipivaloylmethanato)manganese(II); In isopropyl alcohol; at 0 ℃; for 2h; under 760 Torr;

DOI:10.1246/cl.1990.1869

Reference yield: 67.0%

benzyl tiglate → benzyl 2-hydroxy-2-methylbutanoate (54086-29-2,131375-82-1)

Guidance literature:

With phenylsilane; C₂₆H₃₁MnN₂O₆; oxygen; In isopropyl alcohol; at 20 ℃; for 16h;

DOI:10.1039/c9cc03921j

Reference yield: 90.0%

C28H33BiO10 (1370712-69-8) + benzyl 2-hydroxy-2-methylbutanoate (54086-29-2,131375-82-1) → C20H24O5 (1370712-66-5)

Guidance literature:

With N-Methyldicyclohexylamine; oxygen; copper diacetate; at 20 ℃; for 48h; under 760.051 Torr; Molecular sieve;

DOI:10.1055/s-0031-1290205

upstream raw materials:

benzyl tiglate

Downstream raw materials:

C₁₉H₁₉NO₆

C₂₀H₂₂O₅

C₁₉H₁₉NO₃S

C₂₀H₂₄O₅

Refernces

• 1、 Donnelly, Paul S.,North, Andrea J.,Radjah, Natalia Caren,Ricca, Michael,Robertson, Angus,White, Jonathan M.,Rizzacasa, Mark A.. "An effective cis-β-octahedral Mn(iii) SALPN catalyst for the Mukaiyama-Isayama hydration of α,β-unsaturated esters". supporting information. p. 7699 - 7702. Retrieved 2019/07/09.