KNI-10266

Base Information

• Chemical Name: KNI-10266
• CAS No.: 1093409-15-4
• Molecular Formula: C₃₅H₄₀FN₃O₆S
• Molecular Weight: 649.784
• Mol file: 1093409-15-4.mol

Synonyms:

Chemical Property of KNI-10266

Chemical Property:

Purity/Quality:

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Technology Process of KNI-10266

There total 1 articles about KNI-10266 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-N-[(1S,2R)-2-hydroxyindan-1-yl]-3-[(2S,3S)-3-amino-2-hydroxy-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide hydrochloride (1093076-74-4) + 2,6-dimethyl-4-fluoro-phenoxy acetic acid (192725-63-6) → KNI-10266 (1093409-15-4)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; Cooling with ice;

DOI:10.1016/j.bmc.2008.10.011

upstream raw materials:

(R)-N-[(1S,2R)-2-hydroxyindan-1-yl]-3-[(2S,3S)-3-amino-2-hydroxy-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide hydrochloride

2,6-dimethyl-4-fluoro-phenoxy acetic acid