(2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol

Base Information

• Chemical Name: (2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol
• CAS No.: 1123191-35-4
• Molecular Formula: C₂₆H₂₄F₃N₅O₂
• Molecular Weight: 495.504

Synonyms:

Chemical Property of (2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol

There total 1 articles about (2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + (+)-2-{(E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl}-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridine (949170-25-6) → (2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol (1123191-35-4,1123191-36-5,1123191-34-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

Reference yield:

(2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol (1123191-35-4,1123191-36-5,1123191-34-3) → C26H22F3N5O2

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 10h;

Reference yield:

(2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol (1123191-35-4,1123191-36-5,1123191-34-3) → (-)-{2-{(E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl}-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl}methanol + (+)-{2-{(E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl}-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl}methanol

Guidance literature:

With CHIRALPAK IB; In ethanol; hexane; Resolution of racemate;

upstream raw materials:

formaldehyd

(+)-2-{(E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl}-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1123191-35-4 (2-((E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl)-8-(3,4,5-trifluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridin-8-yl)methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send