Technology Process of Benzenamine, N-hexyl-2-methoxy-4-(propylthio)-
There total 8 articles about Benzenamine, N-hexyl-2-methoxy-4-(propylthio)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 2h;
Heating;
DOI:10.1248/cpb.40.351
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaH / 1.) DMF, ice bath, 40 min., 2.) DMF, ice bath, 2 h
2: 52 percent / Na2S2O4 / H2O; methanol / 0.17 h / Heating
3: Et3N, 4-dimethylaminopyridine (DMAP) / tetrahydrofuran / 4 h / Ambient temperature
4: LiAlH4 / tetrahydrofuran / 2 h / Heating
With
dmap; lithium aluminium tetrahydride; sodium dithionite; sodium hydride; triethylamine;
In
tetrahydrofuran; methanol; water;
DOI:10.1248/cpb.40.351
- Guidance literature:
-
Multi-step reaction with 5 steps
1: Et3N / acetone / 2 h / Ambient temperature
2: 1.) Et3N, diphenylphosphoryl azide (DPPA) / 1.) MeCN, reflux, 1 h, 2.) MeCN, reflux, 1 h
3: 85 percent / 35percent aq. KOH / methanol / 3.5 h / Heating
4: Et3N, 4-dimethylaminopyridine (DMAP) / tetrahydrofuran / 4 h / Ambient temperature
5: LiAlH4 / tetrahydrofuran / 2 h / Heating
With
dmap; potassium hydroxide; lithium aluminium tetrahydride; diphenylphosphoranyl azide; triethylamine;
In
tetrahydrofuran; methanol; acetone;
DOI:10.1248/cpb.40.351