<26,27-2H6>cholesteryl benzoate

Base Information

• Chemical Name: <26,27-2H6>cholesteryl benzoate
• CAS No.: 88247-72-7
• Molecular Formula: C₃₄H₅₀O₂
• Molecular Weight: 496.722
• Mol file: 88247-72-7.mol

Synonyms:

Chemical Property of <26,27-2H6>cholesteryl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of <26,27-2H6>cholesteryl benzoate

There total 6 articles about <26,27-2H6>cholesteryl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

<26,27-2H6>desmosteryl benzoate (88247-71-6) → <26,27-2H6>cholesteryl benzoate (88247-72-7)

Guidance literature:

With toluene-4-sulfonic acid hydrazide; In diethylene glycol dimethyl ether; for 2h; Heating;

DOI:10.1039/P19830002563

Reference yield:

24-phenylsulphonylchol-5-en-3β-ol 3-tetrahydropyranyl ether (75303-40-1) → <26,27-2H6>cholesteryl benzoate (88247-72-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 81 percent / 1.) litium di-isopropylamide / tetrahydrofuran / 0.5 h / 0 °C

2: 48 percent / sodium amalgam / tetrahydrofuran; methanol / 4 h / Ambient temperature

3: hydrochloric acid / tetrahydrofuran; methanol / 17 h / Ambient temperature

4: 2.14 g / pyridine / 20 h

5: 46 percent / toluene-p-sulphonohydrazide / bis-(2-methoxy-ethyl) ether / 2 h / Heating

With pyridine; hydrogenchloride; sodium amalgam; toluene-4-sulfonic acid hydrazide; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethylene glycol dimethyl ether;

DOI:10.1039/P19830002563

Reference yield:

benzoyl chloride (98-88-4) → <26,27-2H6>cholesteryl benzoate (88247-72-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.14 g / pyridine / 20 h

2: 46 percent / toluene-p-sulphonohydrazide / bis-(2-methoxy-ethyl) ether / 2 h / Heating

With pyridine; toluene-4-sulfonic acid hydrazide; In diethylene glycol dimethyl ether;

DOI:10.1039/P19830002563

upstream raw materials:

<26,27-2H6>desmosteryl benzoate

24-phenylsulphonylchol-5-en-3β-ol 3-tetrahydropyranyl ether

benzoyl chloride

<26,27-2H6>cholesta-5,24-dien-3β-ol 3-tetrahydropyran-2-yl ether

Downstream raw materials:

(26,26,26,27,27,27-²H₆)cholesterol