3,5-Dibromo-4-chloropyridine

Base Information

• Chemical Name: 3,5-Dibromo-4-chloropyridine
• CAS No.: 13626-17-0
• Molecular Formula: C5H2Br2ClN
• Molecular Weight: 271.339
• Hs Code.: 2933399090
• European Community (EC) Number: 852-183-9
• DSSTox Substance ID: DTXSID70355736
• Nikkaji Number: J1.272.604J
• Wikidata: Q82134786
• Mol file: 13626-17-0.mol

Synonyms:3,5-dibromo-4-chloropyridine;13626-17-0;4-CHLORO-3,5-DIBROMOPYRIDINE;Pyridine, 3,5-dibromo-4-chloro-;MFCD00233993;3,5-dibromo4-chloropyridine;SCHEMBL1938836;DTXSID70355736;XNXHPEUZNXWWCH-UHFFFAOYSA-N;AMY26060;BCP10231;3,5-Dibromo-4-chloropyridine, 98%;AKOS015891847;CS-W021808;PB24627;AC-23106;AS-19836;SY097897;3,5-Dibromo-4-chloropyridine, AldrichCPR;FT-0704669;EN300-194207;AC-907/25004319

Chemical Property of 3,5-Dibromo-4-chloropyridine

Chemical Property:

• Melting Point: 98 °C
• Boiling Point: 256.4±35.0 °C(Predicted)
• PKA: 0.30±0.10(Predicted)
• PSA: 12.89000
• Density: 2.136±0.06 g/cm3(Predicted)
• LogP: 3.26000
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 270.82220
• Heavy Atom Count: 9
• Complexity: 91

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dibromo-4-chloropyridine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=C(C=N1)Br)Cl)Br

Technology Process of 3,5-Dibromo-4-chloropyridine

There total 12 articles about 3,5-Dibromo-4-chloropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5-dibromo-1,4-dihydropyridin-4-one (28419-11-6) → 3,5-dibromo-4-chloro-pyridine (13626-17-0)

Guidance literature:

3,5-dibromo-1,4-dihydropyridin-4-one; With trichlorophosphate; at 100 ℃; for 2h;

With sodium hydrogencarbonate; In water;

Reference yield: 99.0%

3,5-dibromo-4-hydroxypyridine (25813-25-6) → 3,5-dibromo-4-chloro-pyridine (13626-17-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In acetonitrile; for 17h; Cooling with ice; Reflux;

Reference yield: 98.0%

4-amino-3,5-dibromopyridine (84539-34-4) → 3,5-dibromo-4-chloro-pyridine (13626-17-0)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 0 - 20 ℃; for 3h;

DOI:10.1002/chem.201103028

upstream raw materials:

3,5-dibromopyridine-N-oxide

3,5-dibromo-4-hydroxypyridine

3,5-dibromo-4-chloro-pyridine-2-carboxylic acid

sulfuryl dichloride

Downstream raw materials:

3,5-dibromo-pyridine-4-thiol

3,5-dibromopyridine-4-sulfonic acid

(+/-)-3-bromo-4-chloro-5-(2-phenylnaphthalen-1-yl)pyridine

{3-[2-(3,5-dimethylphenyl)naphthalen-1-yl]pyridin-4-yl}diethylamine