3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-phenyl-, methyl ester, trans-

Base Information

• Chemical Name: 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-phenyl-, methyl ester, trans-
• CAS No.: 136285-97-7
• Molecular Formula: C₁₆H₂₀O₂
• Molecular Weight: 244.334
• Mol file: 136285-97-7.mol

Synonyms:

Chemical Property of 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-phenyl-, methyl ester, trans-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-phenyl-, methyl ester, trans-

There total 6 articles about 3-Cyclohexene-1-carboxylic acid, 3,4-dimethyl-6-phenyl-, methyl ester, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

Methyl cinnamate (103-26-4,1754-62-7) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → 3,4-dimethyl-6t-phenyl-cyclohex-3-ene-r-carboxylic acid methyl ester (108774-33-0,136285-97-7,136286-02-7)

Guidance literature:

With C₁₂₀H₈₁F₂₆N₃O₈P₂S₂; (2-methylallyl )triisopropylsilane; at -10 - 0 ℃; for 132h; Concentration; Reagent/catalyst; stereoselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.8b07092

Reference yield: 50.0%

2,3-dimethyl-buta-1,3-diene (513-81-5) → (1S,6S)-3,4-Dimethyl-6-phenyl-cyclohex-3-enecarboxylic acid methyl ester (108774-33-0,136285-97-7,136286-02-7) + (2S,4S)-2-Isopropenyl-2-methyl-4-phenyl-cyclopentanone

Guidance literature:

2,3-dimethyl-buta-1,3-diene; (E)-[(CO)5W=C(OMe)CH=CHPh]; With 2,6-di-tert-butyl-4-methyl-phenol; In toluene; at 80 ℃; for 60h;

With hydrogenchloride; In tetrahydrofuran; at 20 ℃;

DOI:10.1002/anie.200390087

Reference yield: 49.0%

C116H81F18N3O8P2S2 + Methyl cinnamate (103-26-4,1754-62-7) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → 3,4-dimethyl-6t-phenyl-cyclohex-3-ene-r-carboxylic acid methyl ester (108774-33-0,136285-97-7,136286-02-7) + C117H83F18N3O8P2S2

Guidance literature:

With (2-methylallyl )triisopropylsilane; In neat (no solvent); at 60 ℃; for 432h; Sealed tube; Inert atmosphere;

DOI:10.1021/jacs.8b07092

upstream raw materials:

Methyl cinnamate

2,3-dimethyl-buta-1,3-diene

triisopropyl((1-methoxy-2-methylprop-1-en-1-yl)oxy)silane