methyl alectorialate

Base Information

• Chemical Name: methyl alectorialate
• CAS No.: 28789-24-4
• Molecular Formula: C₁₉H₁₈O₉
• Molecular Weight: 390.347
• Mol file: 28789-24-4.mol

Synonyms:

Chemical Property of methyl alectorialate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl alectorialate

There total 10 articles about methyl alectorialate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

methyl 6-bromomethyl-2,4-dihydroxy-3-methylbenzoate (114973-02-3) + potassium haematommate (114973-10-3) → methyl alectorialate (28789-24-4)

Guidance literature:

In N,N-dimethyl acetamide; for 12h; Ambient temperature;

Reference yield:

3,5-dimethoxybenzyl alcohol (705-76-0) → methyl alectorialate (28789-24-4)

Guidance literature:

Multi-step reaction with 7 steps

1: 1.) sodium hydride / 1.) dimethyl sulfoxide, 1 h, 2.) dimethyl sulfoxide, RT, 1 h

2: 1.) phenyllithium / 1.) ether, RT, 24 h, 2.) ether, RT, 1.5 h

3: 84 percent / N-bromosuccinimide / CHCl₃; CCl₄ / 1.) 0 deg C, 1 h, 2.) RT, 2 h

4: 1.) phenyllithium / 1.) ether, RT, 24 h, 2.) ether, a) -78 deg C, 1 h, b) from -78 deg C to RT, 1 h

5: 88 percent / diethyl ether / 0.03 h

6: 51 percent / boron tribromide / 1.) -78 deg C, 0.5 h, 2.) RT, 0.5 h

7: 23 percent / N,N-dimethyl-acetamide / 12 h / Ambient temperature

With N-Bromosuccinimide; boron tribromide; sodium hydride; phenyllithium; In tetrachloromethane; diethyl ether; chloroform; N,N-dimethyl acetamide;

Reference yield:

3,5-dimethoxy-4-methylphenylmethyl alcohol (35052-27-8) → methyl alectorialate (28789-24-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) sodium hydride / 1.) dimethyl sulfoxide, 1 h, 2.) dimethyl sulfoxide, RT, 1 h

2: 84 percent / N-bromosuccinimide / CHCl₃; CCl₄ / 1.) 0 deg C, 1 h, 2.) RT, 2 h

3: 1.) phenyllithium / 1.) ether, RT, 24 h, 2.) ether, a) -78 deg C, 1 h, b) from -78 deg C to RT, 1 h

4: 88 percent / diethyl ether / 0.03 h

5: 51 percent / boron tribromide / 1.) -78 deg C, 0.5 h, 2.) RT, 0.5 h

6: 23 percent / N,N-dimethyl-acetamide / 12 h / Ambient temperature

With N-Bromosuccinimide; boron tribromide; sodium hydride; phenyllithium; In tetrachloromethane; diethyl ether; chloroform; N,N-dimethyl acetamide;

upstream raw materials:

methyl 6-bromomethyl-2,4-dihydroxy-3-methylbenzoate

potassium haematommate

3,5-dimethoxybenzyl alcohol

3,5-dimethoxy-4-methylphenylmethyl alcohol