35052-27-8

Usage

Uses

Used in Pharmaceutical Industry:
(3,5-Dimethoxy-4-methylphenyl)methanol is used as an intermediate in the synthesis of 8,10-Dihydroxy-cannabinol (D448803), a degradation compound of Δ9-Tetrahydrocannabinol (THC) (T293200). THC is the principal active constituent of cannabis, known for its psychoactive and medicinal properties. The synthesis of D448803 from (3,5-dimethoxy-4-methylphenyl)methanol allows for the production of compounds with potential therapeutic applications, particularly in the treatment of various medical conditions such as chronic pain, multiple sclerosis, and epilepsy.
Used in Chemical Synthesis:
(3,5-Dimethoxy-4-methylphenyl)methanol can also be used as a building block in the synthesis of various other organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structural features make it a valuable starting material for the development of novel molecules with diverse applications.

Upstream product

• 61040-81-1 4-methyl-3,5-dimethoxybenzoic acid 

Downstream Products

• 110451-88-2 2-iodo-3,5-dimethoxy-4-methylbenzyl alcohol 
• 114972-96-2 2,6-dimethoxy-4-methoxymethyltoluene 
• 1011-27-4 3,5-dimethoxy-4-methylbenzaldehyde 
• 110452-01-2 6-hydroxymethyl-2,4-dimethoxy-3-methylbenzonitrile 
• 55483-02-8 alectorialin 
• 114972-99-5 2,4-dimethoxy-6-methoxymethyl-3-methylbenzoic acid 
• 114973-00-1 methyl 2,4-dimethoxy-6-methoxymethyl-3-methylbenzoate 
• 114973-01-2 methyl 6-bromomethyl-2-hydroxy-4-methoxy-3-methylbenzoate 
• 114973-02-3 methyl 6-bromomethyl-2,4-dihydroxy-3-methylbenzoate 
• 114972-98-4 3-bromo-2,6-dimethoxy-4-methoxymethyltoluene 
• 114973-11-4 4-bromomethyl-2,6-dihydroxytoluene 
• 28789-24-4 methyl alectorialate 
• 55483-01-7 5,7-Dihydroxy-6-methyl-1(3H)-isobenzofuranon 
• 187104-64-9 3,7-dimethyl-8 methoxy-6-phenylthiomethoxyisochroman 

Relevant academic research and scientific papers

Tandem Chloropalladation/Cyclization and Dearomative Cyclization toward Functionalized Tricyclic Bridged [3.2.1] Skeleton Compounds

A palladium-catalyzed tandem reaction is reported that involves chloropalladation/cyclization and dearomative cyclization to construct a tricyclic bridged [3.2.1] carbocyclic-skeleton and oxa- and aza-skeletons. In this domino process, a level of ring strain and other competitive reactions, i.e., protonolysis, β-hydride elimination, and chlorination of the C-Pd bond, were suppressed to the lowest level under mild reaction conditions.

Benzothiazines in synthesis. Eight-membered ring formation in an intramolecular Friedel-Crafts reaction

Treatment of certain benzothiazines bearing allylic bromides side chains with indium tribromide resulted in the formation of eight-membered rings in addition to the expected six-membered rings.

NOVEL HETEROCYCLIC COMPOUNDS AS HSP90-INHIBITORS

Novel heterocyclic compounds are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agent. Method of synthesis and use of such compounds are also described.