Diethyl 2-(2-(2-nitrophenyl)hydrazono)malonate

Base Information

• Chemical Name: Diethyl 2-(2-(2-nitrophenyl)hydrazono)malonate
• CAS No.: 13631-92-0
• Molecular Formula: C₁₃H₁₅N₃O₆
• Molecular Weight: 309.279
• European Community (EC) Number: 688-778-3
• Mol file: 13631-92-0.mol

Synonyms:13631-92-0;Diethyl 2-(2-(2-nitrophenyl)hydrazono)malonate;diethyl 2-[(2-nitrophenyl)hydrazinylidene]propanedioate;1,3-DIETHYL 2-[2-(2-NITROPHENYL)HYDRAZIN-1-YLIDENE]PROPANEDIOATE;2-((2-NITRO-PHENYL)-HYDRAZONO)-MALONIC ACID DIETHYL ESTER;AKOS000507747;CS-0246516;Diethyl2-(2-(2-nitrophenyl)hydrazono)malonate;EN300-332123;DIETHYL KETOMALONATE, 2-NITROPHENYLHYDRAZONE

Chemical Property of Diethyl 2-(2-(2-nitrophenyl)hydrazono)malonate

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 309.09608521
• Heavy Atom Count: 22
• Complexity: 426

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(=NNC1=CC=CC=C1[N+](=O)[O-])C(=O)OCC

Technology Process of Diethyl 2-(2-(2-nitrophenyl)hydrazono)malonate

There total 5 articles about Diethyl 2-(2-(2-nitrophenyl)hydrazono)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitrobenzenediazonium chloride (119-66-4) + diethyl malonate (105-53-3) → diethyl 2-(o-nitrophenylhydrazono)propanedioate (13631-92-0)

Guidance literature:

With sodium acetate; In methanol; at 0 ℃;

Reference yield:

2-Nitrophenyldiazonium (25910-37-6) + diethyl malonate (105-53-3) → diethyl 2-(o-nitrophenylhydrazono)propanedioate (13631-92-0)

Guidance literature:

With ethanol; zinc(II) chloride;

Reference yield:

2-nitro-aniline (88-74-4) + diethyl malonate (105-53-3) → diethyl 2-(o-nitrophenylhydrazono)propanedioate (13631-92-0)

Guidance literature:

With hydrogenchloride; sodium acetate; sodium nitrite; Multistep reaction; 1.) water, 0 deg C, 2.) acetone, 6 h;

upstream raw materials:

2-Nitrophenyldiazonium

diethyl malonate

2-nitroaniline hydrochloride

2-nitro-aniline

Downstream raw materials:

Mesoxalylchlorid-2-nitrophenylhydrazon

2-(o-nitrophenylhydrazono)propandioic acid