Cbz-ΔGln-OMe

Base Information

Chemical Name:Cbz-ΔGln-OMe
CAS No.:130680-64-7
Molecular Formula:C₁₄H₁₆N₂O₅
Molecular Weight:292.291
Hs Code.:

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Suppliers and Price of Cbz-ΔGln-OMe

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cbz-ΔGln-OMe

Chemical Property:

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Technology Process of Cbz-ΔGln-OMe

There total 3 articles about Cbz-ΔGln-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 130680-61-4
(Z)-Cbz-ΔGlu(OSu)-OMe

: 130680-64-7
Cbz-ΔGln-OMe

Guidance literature:: With ammonium hydroxide; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1248/cpb.38.2020

Reference yield:

: 96658-30-9
methyl γ-methyl-α-(N-benzyloxycarbonyl)-α-dehydroglutamate

: 130680-64-7
Cbz-ΔGln-OMe

Guidance literature:: Multi-step reaction with 3 steps

1: 54 percent / aq. LiOH / H₂O; dioxane / 3 h

2: 100 percent / DCC / tetrahydrofuran

3: 57 percent / 28percent NH₃ aq. / tetrahydrofuran / 1 h / Ambient temperature

With lithium hydroxide; ammonium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1248/cpb.38.2020

Reference yield:

: 130680-59-0
Cbz-ΔGlu-OMe

: 130680-64-7
Cbz-ΔGln-OMe

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / DCC / tetrahydrofuran

2: 57 percent / 28percent NH₃ aq. / tetrahydrofuran / 1 h / Ambient temperature

With ammonium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran;
DOI:10.1248/cpb.38.2020